Literature DB >> 11602767

Sequences adjacent to oriP improve the persistence of Epstein-Barr virus-based episomes in B cells.

R E White1, R Wade-Martins, M R James.   

Abstract

Epstein-Barr virus (EBV) oriP and the EBV nuclear antigen 1 (EBNA-1) protein allow persistence of EBV-based episomes. A nuclear matrix attachment region (MAR) spans oriP and the adjacent region of the EBV genome containing the EBV-expressed RNAs. Here, we show that episomes with the MAR are retained significantly more efficiently in EBV-positive B cells than episomes containing oriP alone.

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Year:  2001        PMID： 11602767      PMCID： PMC114707          DOI： 10.1128/JVI.75.22.11249-11252.2001

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  20 in total

1.  Variant chromatin structure of the oriP region of Epstein-Barr virus and regulation of EBER1 expression by upstream sequences and oriP.

Authors:  B Wensing; A Stühler; P Jenkins; M Hollyoake; C E Karstegl; P J Farrell
Journal:  J Virol       Date:  2001-07       Impact factor: 5.103

2.  Establishment of an oriP replicon is dependent upon an infrequent, epigenetic event.

Authors:  E R Leight; B Sugden
Journal:  Mol Cell Biol       Date:  2001-07       Impact factor: 4.272

3.  Stable correction of a genetic deficiency in human cells by an episome carrying a 115 kb genomic transgene.

Authors:  R Wade-Martins; R E White; H Kimura; P R Cook; M R James
Journal:  Nat Biotechnol       Date:  2000-12       Impact factor: 54.908

4.  A cis-acting element from the Epstein-Barr viral genome that permits stable replication of recombinant plasmids in latently infected cells.

Authors:  J Yates; N Warren; D Reisman; B Sugden
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

5.  Oncogenic role of Epstein-Barr virus-encoded RNAs in Burkitt's lymphoma cell line Akata.

Authors:  J Komano; S Maruo; K Kurozumi; T Oda; K Takada
Journal:  J Virol       Date:  1999-12       Impact factor: 5.103

6.  Initiation of DNA replication within oriP is dispensable for stable replication of the latent Epstein-Barr virus chromosome after infection of established cell lines.

Authors:  P Norio; C L Schildkraut; J L Yates
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

7.  Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cells.

Authors:  J L Yates; N Warren; B Sugden
Journal:  Nature       Date:  1985 Feb 28-Mar 6       Impact factor: 49.962

8.  Long-term stability of large insert genomic DNA episomal shuttle vectors in human cells.

Authors:  R Wade-Martins; J Frampton; M R James
Journal:  Nucleic Acids Res       Date:  1999-04-01       Impact factor: 16.971

9.  Identification of a rare Epstein-Barr virus variant that enhances early antigen expression in Raji cells.

Authors:  M Rabson; L Heston; G Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

10.  Maintenance of Epstein-Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1.

Authors:  S C Hung; M S Kang; E Kieff
Journal:  Proc Natl Acad Sci U S A       Date:  2001-02-06       Impact factor: 11.205
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