| Literature DB >> 11602761 |
B N Lilley1, H L Ploegh, R S Tirabassi.
Abstract
Several herpesviruses encode Fc receptors that may play a role in preventing antibody-mediated clearance of the virus in vivo. Human cytomegalovirus (HCMV) induces an Fc-binding activity in cells upon infection, but the gene that encodes this Fc-binding protein has not been identified. Here, we demonstrate that the HCMV AD169 open reading frame TRL11 and its identical copy, IRL11, encode a type I membrane glycoprotein that possesses IgG Fc-binding capabilities.Entities:
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Year: 2001 PMID: 11602761 PMCID: PMC114701 DOI: 10.1128/JVI.75.22.11218-11221.2001
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103