Literature DB >> 11600376

Cloning and biochemical characterization of FOX-5, an AmpC-type plasmid-encoded beta-lactamase from a New York City Klebsiella pneumoniae clinical isolate.

A M Queenan1, S Jenkins, K Bush.   

Abstract

Klebsiella pneumoniae 5064, isolated in New York, carried plasmid-mediated resistance to multiple beta-lactams and was unresponsive to clavulanic acid. The beta-lactamase gene responsible for cephalosporin resistance encoded FOX-5, with 96 to 97% amino acid identities to other members of the FOX family of beta-lactamases. The bla(FOX-5) coding region was located next to a transposase gene from the Aeromonas salmonicida insertion element ISAS2.

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Year:  2001        PMID： 11600376      PMCID： PMC90802          DOI： 10.1128/AAC.45.11.3189-3194.2001

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  22 in total

1.  A novel type of AmpC beta-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia.

Authors:  A Bauernfeind; I Schneider; R Jungwirth; H Sahly; U Ullmann
Journal:  Antimicrob Agents Chemother       Date:  1999-08       Impact factor: 5.191

2.  Effective cooling allows sonication to be used for liberation of beta-lactamases from gram negative bacteria.

Authors:  K Bush; S B Singer
Journal:  J Antimicrob Chemother       Date:  1989-07       Impact factor: 5.790

3.  The graphical determination of K m and K i .

Authors:  M Dixon
Journal:  Biochem J       Date:  1972-08       Impact factor: 3.857

4.  Identification of beta-lactamases by analytical isoelectric focusing: correlation with bacterial taxonomy.

Authors:  M Matthew; A M Harris
Journal:  J Gen Microbiol       Date:  1976-05

5.  ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

Authors:  B Jaurin; T Grundström
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

6.  Occurrence and detection of AmpC beta-lactamases among Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis isolates at a veterans medical center.

Authors:  P E Coudron; E S Moland; K S Thomson
Journal:  J Clin Microbiol       Date:  2000-05       Impact factor: 5.948

7.  Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria.

Authors:  R B Sykes; D P Bonner; K Bush; N H Georgopapadakou
Journal:  Antimicrob Agents Chemother       Date:  1982-01       Impact factor: 5.191

8.  Identification of a novel plasmid-mediated beta-lactamase with chromosomal cephalosporinase characteristics from Klebsiella pneumoniae.

Authors:  L S Tzouvelekis; E Tzelepi; A F Mentis; A Tsakris
Journal:  J Antimicrob Chemother       Date:  1993-05       Impact factor: 5.790

9.  Plasmid-mediated AmpC-type beta-lactamase isolated from Klebsiella pneumoniae confers resistance to broad-spectrum beta-lactams, including moxalactam.

Authors:  T Horii; Y Arakawa; M Ohta; S Ichiyama; R Wacharotayankun; N Kato
Journal:  Antimicrob Agents Chemother       Date:  1993-05       Impact factor: 5.191

10.  Novel plasmid-mediated beta-lactamase (MIR-1) conferring resistance to oxyimino- and alpha-methoxy beta-lactams in clinical isolates of Klebsiella pneumoniae.

Authors:  G A Papanicolaou; A A Medeiros; G A Jacoby
Journal:  Antimicrob Agents Chemother       Date:  1990-11       Impact factor: 5.191
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  22 in total

1.  Detection of plasmid-mediated AmpC beta-lactamase genes in clinical isolates by using multiplex PCR.

Authors:  F Javier Pérez-Pérez; Nancy D Hanson
Journal:  J Clin Microbiol       Date:  2002-06       Impact factor: 5.948

2.  Horizontal transfer of blaCMY-bearing plasmids among clinical Escherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydrolyzing CMY-19.

Authors:  Jun-ichi Wachino; Hiroshi Kurokawa; Satowa Suzuki; Kunikazu Yamane; Naohiro Shibata; Kouji Kimura; Yasuyoshi Ike; Yoshichika Arakawa
Journal:  Antimicrob Agents Chemother       Date:  2006-02       Impact factor: 5.191

3.  Multiplex asymmetric PCR-based oligonucleotide microarray for detection of drug resistance genes containing single mutations in Enterobacteriaceae.

Authors:  Ling-Xiang Zhu; Zhi-Wei Zhang; Dong Liang; Di Jiang; Can Wang; Ning Du; Qiong Zhang; Keith Mitchelson; Jing Cheng
Journal:  Antimicrob Agents Chemother       Date:  2007-07-23       Impact factor: 5.191

4.  Multiple Copies of qnrA1 on an IncA/C2 Plasmid Explain Enhanced Quinolone Resistance in an Escherichia coli Mutant.

Authors:  Laura Vinué; Mohamad R A Sater; Ian Herriott; Miriam H Huntley; George A Jacoby; David C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2019-07-25       Impact factor: 5.191

5.  Efficacy of cefepime and imipenem in experimental murine pneumonia caused by porin-deficient Klebsiella pneumoniae producing CMY-2 beta-Lactamase.

Authors:  Cristina Pichardo; José Manuel Rodríguez-Martínez; María E Pachón-Ibañez; Carmen Conejo; José Ibáñez-Martínez; Luis Martínez-Martínez; Jerónimo Pachón; Alvaro Pascual
Journal:  Antimicrob Agents Chemother       Date:  2005-08       Impact factor: 5.191

6.  Beta-lactamases in ampicillin-resistant Escherichia coli isolates from foods, humans, and healthy animals.

Authors:  Laura Briñas; Myriam Zarazaga; Yolanda Sáenz; Fernanda Ruiz-Larrea; Carmen Torres
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

7.  Characterization of a novel plasmid-mediated cephalosporinase (CMY-9) and its genetic environment in an Escherichia coli clinical isolate.

Authors:  Yohei Doi; Naohiro Shibata; Keigo Shibayama; Kazunari Kamachi; Hiroshi Kurokawa; Keiko Yokoyama; Tetsuya Yagi; Yoshichika Arakawa
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

8.  Occurrence of extended-spectrum and AmpC beta-lactamases in bloodstream isolates of Klebsiella pneumoniae: isolates harbor plasmid-mediated FOX-5 and ACT-1 AmpC beta-lactamases.

Authors:  Philip E Coudron; Nancy D Hanson; Michael W Climo
Journal:  J Clin Microbiol       Date:  2003-02       Impact factor: 5.948

9.  A kinetic analysis of the inhibition of FOX-4 β-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic β-lactams and carbapenems.

Authors:  Krisztina M Papp-Wallace; Susana Mallo; Christopher R Bethel; Magdalena A Taracila; Andrea M Hujer; Ana Fernández; Julian A Gatta; Kerri M Smith; Yan Xu; Malcolm G P Page; Eric Desarbre; Germán Bou; Robert A Bonomo
Journal:  J Antimicrob Chemother       Date:  2013-11-13       Impact factor: 5.790

10.  New method for laboratory detection of AmpC beta-lactamases in Escherichia coli and Klebsiella pneumoniae.

Authors:  K Nasim; S Elsayed; J D D Pitout; J Conly; D L Church; D B Gregson
Journal:  J Clin Microbiol       Date:  2004-10       Impact factor: 5.948
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