Literature DB >> 11598100

Effect of SpeB and EndoS from Streptococcus pyogenes on human immunoglobulins.

M Collin1, A Olsén.   

Abstract

Streptococcus pyogenes secretes a specific immunoglobulin G (IgG)-protease, SpeB, as well as the IgG glycan-hydrolyzing enzyme EndoS. Here we show that SpeB also degrades IgA, IgM, IgD, and IgE. We also show that EndoS only hydrolyzes the glycan moiety on native but not denatured IgG. Thus, SpeB has a broad immunoglobulin-degrading activity, while EndoS is highly specific for IgG.

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Year:  2001        PMID： 11598100      PMCID： PMC100124          DOI： 10.1128/IAI.69.11.7187-7189.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  25 in total

1.  Enzymatic deglycosylation of asparagine-linked glycans: purification, properties, and specificity of oligosaccharide-cleaving enzymes from Flavobacterium meningosepticum.

Authors:  A L Tarentino; T H Plummer
Journal:  Methods Enzymol       Date:  1994       Impact factor: 1.600

2.  Isolation and characterization of erythrogenic toxins. V. Communication: identity of erythrogenic toxin type B and streptococcal proteinase precursor.

Authors:  D Gerlach; H Knöll; W Köhler; J H Ozegowski; V Hríbalova
Journal:  Zentralbl Bakteriol Mikrobiol Hyg A       Date:  1983-09

3.  Recognition of IgG by Fcgamma receptor. The role of Fc glycosylation and the binding of peptide inhibitors.

Authors:  S Radaev; P D Sun
Journal:  J Biol Chem       Date:  2001-01-31       Impact factor: 5.157

4.  Inactivation of Streptococcus pyogenes extracellular cysteine protease significantly decreases mouse lethality of serotype M3 and M49 strains.

Authors:  S Lukomski; S Sreevatsan; C Amberg; W Reichardt; M Woischnik; A Podbielski; J M Musser
Journal:  J Clin Invest       Date:  1997-06-01       Impact factor: 14.808

5.  A protein sequenator.

Authors:  P Edman; G Begg
Journal:  Eur J Biochem       Date:  1967-03

6.  Effect of group A streptococcal cysteine protease on invasion of epithelial cells.

Authors:  P J Tsai; C F Kuo; K Y Lin; Y S Lin; H Y Lei; F F Chen; J R Wang; J J Wu
Journal:  Infect Immun       Date:  1998-04       Impact factor: 3.441

7.  Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.

Authors:  V Kapur; M W Majesky; L L Li; R A Black; J M Musser
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

8.  A conserved Streptococcus pyogenes extracellular cysteine protease cleaves human fibronectin and degrades vitronectin.

Authors:  V Kapur; S Topouzis; M W Majesky; L L Li; M R Hamrick; R J Hamill; J M Patti; J M Musser
Journal:  Microb Pathog       Date:  1993-11       Impact factor: 3.738

9.  A nonradioactive biochemical characterization of membrane proteins using enhanced chemiluminescence.

Authors:  S A Nesbitt; M A Horton
Journal:  Anal Biochem       Date:  1992-11-01       Impact factor: 3.365

10.  Characterization of immunoglobulin G-degrading proteases of Prevotella intermedia and Prevotella nigrescens.

Authors:  H J Jansen; D Grenier; J S Van der Hoeven
Journal:  Oral Microbiol Immunol       Date:  1995-06
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  74 in total

Review 1.  Extracellular enzymes with immunomodulating activities: variations on a theme in Streptococcus pyogenes.

Authors:  Mattias Collin; Arne Olsén
Journal:  Infect Immun       Date:  2003-06       Impact factor: 3.441

2.  The Second Messenger c-di-AMP Regulates Diverse Cellular Pathways Involved in Stress Response, Biofilm Formation, Cell Wall Homeostasis, SpeB Expression, and Virulence in Streptococcus pyogenes.

Authors:  Tazin Fahmi; Sabrina Faozia; Gary C Port; Kyu Hong Cho
Journal:  Infect Immun       Date:  2019-05-21       Impact factor: 3.441

3.  Remarkable transglycosylation activity of glycosynthase mutants of endo-D, an endo-β-N-acetylglucosaminidase from Streptococcus pneumoniae.

Authors:  Shu-Quan Fan; Wei Huang; Lai-Xi Wang
Journal:  J Biol Chem       Date:  2012-02-08       Impact factor: 5.157

4.  A new autocatalytic activation mechanism for cysteine proteases revealed by Prevotella intermedia interpain A.

Authors:  Noemí Mallorquí-Fernández; Surya P Manandhar; Goretti Mallorquí-Fernández; Isabel Usón; Katarzyna Wawrzonek; Tomasz Kantyka; Maria Solà; Ida B Thøgersen; Jan J Enghild; Jan Potempa; F Xavier Gomis-Rüth
Journal:  J Biol Chem       Date:  2007-11-09       Impact factor: 5.157

5.  Therapeutic potential of deglycosylated antibodies.

Authors:  Max Crispin
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-07       Impact factor: 11.205

6.  T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies.

Authors:  Constanze Hess; André Winkler; Alexandra K Lorenz; Vivien Holecska; Véronique Blanchard; Susanne Eiglmeier; Anna-Lena Schoen; Josephine Bitterling; Alexander D Stoehr; Dominique Petzold; Tim Schommartz; Maria M M Mertes; Carolin T Schoen; Ben Tiburzy; Anne Herrmann; Jörg Köhl; Rudolf A Manz; Michael P Madaio; Markus Berger; Hedda Wardemann; Marc Ehlers
Journal:  J Clin Invest       Date:  2013-08-27       Impact factor: 14.808

7.  In vivo enzymatic modulation of IgG glycosylation inhibits autoimmune disease in an IgG subclass-dependent manner.

Authors:  Heike Albert; Mattias Collin; Diana Dudziak; Jeffrey V Ravetch; Falk Nimmerjahn
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-24       Impact factor: 11.205

8.  Cysteine proteinase from Streptococcus pyogenes enables evasion of innate immunity via degradation of complement factors.

Authors:  Mariko Honda-Ogawa; Taiji Ogawa; Yutaka Terao; Tomoko Sumitomo; Masanobu Nakata; Kazunori Ikebe; Yoshinobu Maeda; Shigetada Kawabata
Journal:  J Biol Chem       Date:  2013-04-15       Impact factor: 5.157

9.  Group A streptococcal cysteine protease cleaves epithelial junctions and contributes to bacterial translocation.

Authors:  Tomoko Sumitomo; Masanobu Nakata; Miharu Higashino; Yutaka Terao; Shigetada Kawabata
Journal:  J Biol Chem       Date:  2013-03-26       Impact factor: 5.157

10.  Identification of a novel host-specific IgM protease in Streptococcus suis.

Authors:  Jana Seele; Alena Singpiel; Christian Spoerry; Ulrich von Pawel-Rammingen; Peter Valentin-Weigand; Christoph G Baums
Journal:  J Bacteriol       Date:  2012-12-14       Impact factor: 3.490
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