Literature DB >> 11598093

Histopathological studies on virulence of dipeptidyl aminopeptidase IV (DPPIV) of Porphyromonas gingivalis in a mouse abscess model: use of a DPPIV-deficient mutant.

H Yagishita1, Y Kumagai, K Konishi, Y Takahashi, T Aoba, M Yoshikawa.   

Abstract

To elucidate the role of dipeptidyl aminopeptidase IV (DPPIV) in the virulence of Porphyromonas gingivalis, mice were infected with either a wild-type strain or a DPPIV-deficient mutant using an abscess model. Histopathological analysis of the resulting lesions indicated that DPPIV participates in virulence through the destruction of connective tissue and the less effective mobilization of inflammatory cells.

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Year:  2001        PMID： 11598093      PMCID： PMC100111          DOI： 10.1128/IAI.69.11.7159-7161.2001

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  7 in total

1.  Enzymatic properties of dipeptidyl aminopeptidase IV produced by the periodontal pathogen Porphyromonas gingivalis and its participation in virulence.

Authors:  Y Kumagai; K Konishi; T Gomi; H Yagishita; A Yajima; M Yoshikawa
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

2.  Implantation of Bacteroides gingivalis in nonhuman primates initiates progression of periodontitis.

Authors:  S C Holt; J Ebersole; J Felton; M Brunsvold; K S Kornman
Journal:  Science       Date:  1988-01-01       Impact factor: 47.728

Review 3.  The unique properties of dipeptidyl-peptidase IV (DPP IV / CD26) and the therapeutic potential of DPP IV inhibitors.

Authors:  K Augustyns; G Bal; G Thonus; A Belyaev; X M Zhang; W Bollaert; A M Lambeir; C Durinx; F Goossens; A Haemers
Journal:  Curr Med Chem       Date:  1999-04       Impact factor: 4.530

Review 4.  Animal models for Porphyromonas gingivalis-mediated periodontal disease.

Authors:  C A Genco; T Van Dyke; S Amar
Journal:  Trends Microbiol       Date:  1998-11       Impact factor: 17.079

5.  Virulence of a Porphyromonas gingivalis W83 mutant defective in the prtH gene.

Authors:  H M Fletcher; H A Schenkein; R M Morgan; K A Bailey; C R Berry; F L Macrina
Journal:  Infect Immun       Date:  1995-04       Impact factor: 3.441

6.  Simultaneous identification of bacterial virulence genes by negative selection.

Authors:  M Hensel; J E Shea; C Gleeson; M D Jones; E Dalton; D W Holden
Journal:  Science       Date:  1995-07-21       Impact factor: 47.728

Review 7.  Pathogenic strategies of the oral anaerobe, Porphyromonas gingivalis.

Authors:  C W Cutler; J R Kalmar; C A Genco
Journal:  Trends Microbiol       Date:  1995-02       Impact factor: 17.079
  7 in total
  10 in total

1.  Identification of a protein subset of the anthrax spore immunome in humans immunized with the anthrax vaccine adsorbed preparation.

Authors:  Indira T Kudva; Robert W Griffin; Jeonifer M Garren; Stephen B Calderwood; Manohar John
Journal:  Infect Immun       Date:  2005-09       Impact factor: 3.441

2.  Molecular mechanism for connective tissue destruction by dipeptidyl aminopeptidase IV produced by the periodontal pathogen Porphyromonas gingivalis.

Authors:  Yumi Kumagai; Hisao Yagishita; Ayako Yajima; Tatsuya Okamoto; Kiyoshi Konishi
Journal:  Infect Immun       Date:  2005-05       Impact factor: 3.441

3.  The contribution of Tannerella forsythia dipeptidyl aminopeptidase IV in the breakdown of collagen.

Authors:  Susan Yost; Ana E Duran-Pinedo
Journal:  Mol Oral Microbiol       Date:  2018-10-05       Impact factor: 3.563

4.  Glycolytic enzymes associated with the cell surface of Streptococcus pneumoniae are antigenic in humans and elicit protective immune responses in the mouse.

Authors:  E Ling; G Feldman; M Portnoi; R Dagan; K Overweg; F Mulholland; V Chalifa-Caspi; J Wells; Y Mizrachi-Nebenzahl
Journal:  Clin Exp Immunol       Date:  2004-11       Impact factor: 4.330

5.  Cloning, purification, and enzymatic properties of dipeptidyl peptidase IV from the swine pathogen Streptococcus suis.

Authors:  Marie-Claude Jobin; Gabriela Martinez; Julie Motard; Marcelo Gottschalk; Daniel Grenier
Journal:  J Bacteriol       Date:  2005-01       Impact factor: 3.490

6.  Secreted dipeptidyl peptidase IV activity in the dimorphic fungal pathogen Histoplasma capsulatum.

Authors:  Kendal G Cooper; Jon P Woods
Journal:  Infect Immun       Date:  2009-04-06       Impact factor: 3.441

7.  Non-Coding RNAs are Differentially Expressed by Nocardia brasiliensis in Vitro and in Experimental Actinomycetoma.

Authors:  Josué S Cruz-Rabadán; Juan Miranda-Ríos; Guadalupe Espín-Ocampo; Luis J Méndez-Tovar; Héctor Rubén Maya-Pineda; Francisca Hernández-Hernández
Journal:  Open Microbiol J       Date:  2017-06-30

Review 8.  Inherently and Conditionally Essential Protein Catabolism Genes of Porphyromonas gingivalis.

Authors:  Daniel P Miller; David A Scott
Journal:  Trends Microbiol       Date:  2020-10-15       Impact factor: 17.079

9.  Histoplasma capsulatum encodes a dipeptidyl peptidase active against the mammalian immunoregulatory peptide, substance P.

Authors:  Kendal G Cooper; Robert Zarnowski; Jon P Woods
Journal:  PLoS One       Date:  2009-04-22       Impact factor: 3.240

10.  Enolase and dipeptidyl peptidase IV protein sub-unit vaccines are not protective against a lethal Streptococcus suis serotype 2 challenge in a mouse model of infection.

Authors:  Audrey Dumesnil; Léa Martelet; Daniel Grenier; Jean-Philippe Auger; Josée Harel; Eric Nadeau; Marcelo Gottschalk
Journal:  BMC Vet Res       Date:  2019-12-10       Impact factor: 2.741
  10 in total

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