Literature DB >> 11595281

PEGylated polycyanoacrylate nanoparticles as vector for drug delivery in prion diseases.

P Calvo1, B Gouritin, I Brigger, C Lasmezas, J Deslys, A Williams, J P Andreux, D Dormont, P Couvreur.   

Abstract

PEGylated polymeric nanoparticles are hereby presented as a potential efficient drug carrier for the delivery of active therapeutic molecules in prion experimental diseases. Based on their blood long-circulating characteristics, these PEGylated particles made by the amphiphilic copolymer poly [methoxy poly(ethylene glycol) cyanoacrylate-co-hexadecyl cyanoacrylate] (PEG-PHDCA), showed comparatively conventional non-PEGylated nanoparticles, a higher uptake by the spleen and the brain which are both the target tissues of PrPres accumulation in scrapie infected animals.

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Year:  2001        PMID: 11595281     DOI: 10.1016/s0165-0270(01)00450-2

Source DB:  PubMed          Journal:  J Neurosci Methods        ISSN: 0165-0270            Impact factor:   2.390


  19 in total

1.  Future prospects of nanoparticles on brain targeted drug delivery.

Authors:  C Chakraborty; B Sarkar; C H Hsu; Z H Wen; C S Lin; P C Shieh
Journal:  J Neurooncol       Date:  2008-12-02       Impact factor: 4.130

Review 2.  Nanotechnology-based drug delivery systems for targeting, imaging and diagnosis of neurodegenerative diseases.

Authors:  Sibel Bozdağ Pehlivan
Journal:  Pharm Res       Date:  2013-10       Impact factor: 4.200

Review 3.  Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging.

Authors:  Sonu Bhaskar; Furong Tian; Tobias Stoeger; Wolfgang Kreyling; Jesús M de la Fuente; Valeria Grazú; Paul Borm; Giovani Estrada; Vasilis Ntziachristos; Daniel Razansky
Journal:  Part Fibre Toxicol       Date:  2010-03-03       Impact factor: 9.400

4.  Drug delivery systems: Advanced technologies potentially applicable in personalized treatments.

Authors:  Jorge F Coelho; Paula C Ferreira; Patricia Alves; Rosemeyre Cordeiro; Ana C Fonseca; Joana R Góis; Maria H Gil
Journal:  EPMA J       Date:  2010-04-10       Impact factor: 6.543

Review 5.  Implications of peptide assemblies in amyloid diseases.

Authors:  Pu Chun Ke; Marc-Antonie Sani; Feng Ding; Aleksandr Kakinen; Ibrahim Javed; Frances Separovic; Thomas P Davis; Raffaele Mezzenga
Journal:  Chem Soc Rev       Date:  2017-10-30       Impact factor: 54.564

Review 6.  Neurotheranostics as personalized medicines.

Authors:  Bhavesh D Kevadiya; Brendan M Ottemann; Midhun Ben Thomas; Insiya Mukadam; Saumya Nigam; JoEllyn McMillan; Santhi Gorantla; Tatiana K Bronich; Benson Edagwa; Howard E Gendelman
Journal:  Adv Drug Deliv Rev       Date:  2018-10-26       Impact factor: 15.470

Review 7.  Micellar nanocarriers: pharmaceutical perspectives.

Authors:  V P Torchilin
Journal:  Pharm Res       Date:  2006-11-16       Impact factor: 4.200

8.  Polymeric micelles for acyclovir drug delivery.

Authors:  Alicia J Sawdon; Ching-An Peng
Journal:  Colloids Surf B Biointerfaces       Date:  2014-08-20       Impact factor: 5.268

9.  Uptake mechanism of ApoE-modified nanoparticles on brain capillary endothelial cells as a blood-brain barrier model.

Authors:  Sylvia Wagner; Anja Zensi; Sascha L Wien; Sabrina E Tschickardt; Wladislaw Maier; Tikva Vogel; Franz Worek; Claus U Pietrzik; Jörg Kreuter; Hagen von Briesen
Journal:  PLoS One       Date:  2012-03-01       Impact factor: 3.240

10.  Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumors.

Authors:  Serhii Kostrikov; Kasper B Johnsen; Thomas H Braunstein; Johann M Gudbergsson; Frederikke P Fliedner; Elisabeth A A Obara; Petra Hamerlik; Anders E Hansen; Andreas Kjaer; Casper Hempel; Thomas L Andresen
Journal:  Commun Biol       Date:  2021-07-01
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