| Literature DB >> 11594813 |
Y Zheng1, Q Huo, P Kele, F M Andreopoulos, S M Pham, R M Leblanc.
Abstract
[structure: see text]. A new fluorescent chemosensor for Cu2+ ions was synthesized by modifying the tripeptide glycyl-histidyl-lysine (GHK) with 9-carbonylanthracene via the standard Fmoc solid-phase peptide synthesis method. While significant fluorescence quenching was observed from the molecule upon binding with Cu2+, addition of Fe2+, Co2+, Ni2+, and Zn2+ to the peptide solution caused a minimum fluorescence emission spectral change, indicating a high specificity of this chemosensor for Cu2+ ions. Effects of pH were also investigated.Entities:
Mesh：
Substances：
Year: 2001 PMID： 11594813 DOI： 10.1021/ol0101638
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005