Literature DB >> 11594805

Intramolecular conjugate addition of alkenyl and aryl functions to enones initiated by lithium-iodine exchange.

E Piers1, C L Harrison, C Zetina-Rocha.   

Abstract

[reaction: see text]. Treatment of each of the substrates 20-26, 29, and 46-48 with t-BuLi in THF, in the presence of HMPA and TMSCl, provides good-to-excellent yields of the intramolecular conjugate addition products 30-36, 37, and 49-51, respectively.

Entities:  

Year:  2001        PMID： 11594805     DOI： 10.1021/ol016288u

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Design and synthesis of simplified taxol analogs based on the T-Taxol bioactive conformation.

Authors:  Jielu Zhao; Susan Bane; James P Snyder; Haipeng Hu; Kamalika Mukherjee; Carla Slebodnick; David G I Kingston
Journal:  Bioorg Med Chem       Date:  2011-10-13       Impact factor: 3.641

2.  Short Enantioselective Formal Synthesis of (-)-Platencin.

Authors:  Christian Defieber; Justin T Mohr; Gennadii A Grabovyi; Brian M Stoltz
Journal:  Synthesis (Stuttg)       Date:  2018-07-23       Impact factor: 3.157

3.  Rapid assembly of vinigrol's unique carbocyclic skeleton.

Authors:  Jason G M Morton; Cristian Draghici; Laura D Kwon; Jon T Njardarson
Journal:  Org Lett       Date:  2009-10-15       Impact factor: 6.005
  3 in total

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