Literature DB >> 11592134

Medicinal Chemistry: Challenges and Opportunities.

Günther Wess1, Matthias Urmann, Birgitt Sickenberger.   

Abstract

Year:  2001        PMID： 11592134

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  10 in total

Review 1.  The re-emergence of natural products for drug discovery in the genomics era.

Authors:  Alan L Harvey; RuAngelie Edrada-Ebel; Ronald J Quinn
Journal:  Nat Rev Drug Discov       Date:  2015-01-23       Impact factor: 84.694

Review 2.  G protein-coupled receptor deorphanizations.

Authors:  Olivier Civelli; Rainer K Reinscheid; Yan Zhang; Zhiwei Wang; Robert Fredriksson; Helgi B Schiöth
Journal:  Annu Rev Pharmacol Toxicol       Date:  2012-09-28       Impact factor: 13.820

3.  Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes.

Authors:  Kevin X Rodriguez; Erin N Howe; Emily P Bacher; Miranda Burnette; Jennifer L Meloche; Jayda Meisel; Patricia Schnepp; Xuejuan Tan; Mayland Chang; Jeremiah Zartman; Siyuan Zhang; Brandon L Ashfeld
Journal:  ChemMedChem       Date:  2019-07-01       Impact factor: 3.466

4.  Automated docking with protein flexibility in the design of femtomolar "click chemistry" inhibitors of acetylcholinesterase.

Authors:  Garrett M Morris; Luke G Green; Zoran Radić; Palmer Taylor; K Barry Sharpless; Arthur J Olson; Flavio Grynszpan
Journal:  J Chem Inf Model       Date:  2013-03-29       Impact factor: 4.956

5.  Decoration of dihydropyrimidine and dihydropyridine scaffolds with sugars via Biginelli and Hantzsch multicomponent reactions: an efficient entry to a collection of artificial nucleosides.

Authors:  Alessandro Dondoni; Alessandro Massi
Journal:  Mol Divers       Date:  2003       Impact factor: 2.943

Review 6.  1,4-Dihydropyridines as calcium channel ligands and privileged structures.

Authors:  David J Triggle
Journal:  Cell Mol Neurobiol       Date:  2003-06       Impact factor: 5.046

Review 7.  Ugi-Smiles couplings: new entries to N-aryl carboxamide derivatives.

Authors:  Laurent El Kaïm; Laurence Grimaud
Journal:  Mol Divers       Date:  2009-07-07       Impact factor: 2.943

8.  A practical and efficient approach to imidazo[1,2-a]pyridine-fused isoquinolines through the post-GBB transformation strategy.

Authors:  Taofeng Shao; Zhiming Gong; Tianyi Su; Wei Hao; Chao Che
Journal:  Beilstein J Org Chem       Date:  2017-05-04       Impact factor: 2.883

9.  Eco-friendly methodology to prepare N-heterocycles related to dihydropyridines: microwave-assisted synthesis of alkyl 4-arylsubstituted-6-chloro-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate and 4-arylsubstituted-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-dione.

Authors:  Hortensia Rodríguez; Osnieski Martin; Margarita Suarez; Nazario Martín; Fernando Albericio
Journal:  Molecules       Date:  2011-11-21       Impact factor: 4.411

10.  Computational analysis, alignment and extension of analogue series from medicinal chemistry.

Authors:  Atsushi Yoshimori; Jürgen Bajorath
Journal:  Future Sci OA       Date:  2022-06-28
  10 in total

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