Literature DB >> 11591473

Structural and functional features of eukaryotic mRNA untranslated regions.

G Pesole1, F Mignone, C Gissi, G Grillo, F Licciulli, S Liuni.   

Abstract

The crucial role of the non-coding portion of genomes is now widely acknowledged. In particular, mRNA untranslated regions are involved in many post-transcriptional regulatory pathways that control mRNA localization, stability and translation efficiency. We review in this paper the major structural and compositional features of eukaryotic mRNA untranslated regions and provide some examples of bioinformatic analyses for their functional characterization.

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Year:  2001        PMID： 11591473     DOI： 10.1016/s0378-1119(01)00674-6

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  148 in total

1.  The alternative use of exons 2 and 3 in cathepsin B mRNA controls enzyme trafficking and triggers nuclear fragmentation in human cells.

Authors:  Kathrin Müntener; Roman Zwicky; Gabor Csucs; Antonio Baici
Journal:  Histochem Cell Biol       Date:  2003-01-16       Impact factor: 4.304

2.  HLA-G allelic variants are associated with differences in the HLA-G mRNA isoform profile and HLA-G mRNA levels.

Authors:  Thomas Vauvert F Hviid; Sine Hylenius; Christina Rørbye; Lone G Nielsen
Journal:  Immunogenetics       Date:  2003-04-24       Impact factor: 2.846

Review 3.  MRNA stability and the control of gene expression: implications for human disease.

Authors:  Elysia M Hollams; Keith M Giles; Andrew M Thomson; Peter J Leedman
Journal:  Neurochem Res       Date:  2002-10       Impact factor: 3.996

4.  Patterns in interspecies similarity correlate with nucleotide composition in mammalian 3'UTRs.

Authors:  Svetlana A Shabalina; Aleksey Y Ogurtsov; David J Lipman; Alexey S Kondrashov
Journal:  Nucleic Acids Res       Date:  2003-09-15       Impact factor: 16.971

5.  5' Long serial analysis of gene expression (LongSAGE) and 3' LongSAGE for transcriptome characterization and genome annotation.

Authors:  Chia-Lin Wei; Patrick Ng; Kuo Ping Chiu; Chee Hong Wong; Chin Chin Ang; Leonard Lipovich; Edison T Liu; Yijun Ruan
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-22       Impact factor: 11.205

6.  Gene length and proximity to neighbors affect genome-wide expression levels.

Authors:  Francesca Chiaromonte; Webb Miller; Eric E Bouhassira
Journal:  Genome Res       Date:  2003-11-12       Impact factor: 9.043

7.  Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.

Authors:  Elena Tzouanacou; Susan Tweedie; Valerie Wilson
Journal:  Mol Cell Biol       Date:  2003-12       Impact factor: 4.272

8.  Cloning and characterization of buffalo NANOG gene: alternative transcription start sites, splicing, and polyadenylation in embryonic stem cell-like cells.

Authors:  Natwar Singh; Ruchi Sharma; Aman George; Suresh K Singla; Prabhat Palta; Radhaysham Manik; Manmohan S Chauhan; Dheer Singh
Journal:  DNA Cell Biol       Date:  2011-10-19       Impact factor: 3.311

9.  The BCL-2 5' untranslated region contains an RNA G-quadruplex-forming motif that modulates protein expression.

Authors:  Ramla Shahid; Anthony Bugaut; Shankar Balasubramanian
Journal:  Biochemistry       Date:  2010-09-28       Impact factor: 3.162

10.  Analysis of the 5' untranslated region (5'UTR) of the alcohol oxidase 1 (AOX1) gene in recombinant protein expression in Pichia pastoris.

Authors:  Chris A Staley; Amy Huang; Maria Nattestad; Kristin T Oshiro; Laura E Ray; Tejas Mulye; Zhiguo Harry Li; Thu Le; Justin J Stephens; Seth R Gomez; Allison D Moy; Jackson C Nguyen; Andreas H Franz; Joan Lin-Cereghino; Geoff P Lin-Cereghino
Journal:  Gene       Date:  2012-01-25       Impact factor: 3.688
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