OBJECTIVE: To study the incidence and mortality of coronary heart disease (CHD) and all-cause mortality in a cohort of men followed during 28 years, and their association with serum cholesterol, systolic blood pressure, glycemia, cigarette smoking and body mass index measured at baseline. RESEARCH DESIGN AND METHODS: A cohort of 1,059 men aged 30 to 59 years and free of cardiovascular diseases at baseline in 1968, was examined every five years until 1988. The last examination was performed in 1996. Information was collected in 96.4% of the participants. RESULTS: Incidence and mortality rates from CHD and from all-causes of death per 105 person-years of observation were 499.80, 235.80 and 925.33, respectively. At the end of follow-up, high levels of serum cholesterol and smoking were independently associated with the incidence and mortality from CHD adjusted for age, blood pressure, glycemia and BMI. Serum cholesterol, hyperglycemia and smoking were independently associated with all-cause mortality. CONCLUSIONS: In this industrial cohort of men, with a relatively low incidence of CHD, smoking and serum cholesterol at baseline were independently associated with the incidence of CHD over 28 years of observation.
OBJECTIVE: To study the incidence and mortality of coronary heart disease (CHD) and all-cause mortality in a cohort of men followed during 28 years, and their association with serum cholesterol, systolic blood pressure, glycemia, cigarette smoking and body mass index measured at baseline. RESEARCH DESIGN AND METHODS: A cohort of 1,059 men aged 30 to 59 years and free of cardiovascular diseases at baseline in 1968, was examined every five years until 1988. The last examination was performed in 1996. Information was collected in 96.4% of the participants. RESULTS: Incidence and mortality rates from CHD and from all-causes of death per 105 person-years of observation were 499.80, 235.80 and 925.33, respectively. At the end of follow-up, high levels of serum cholesterol and smoking were independently associated with the incidence and mortality from CHD adjusted for age, blood pressure, glycemia and BMI. Serum cholesterol, hyperglycemia and smoking were independently associated with all-cause mortality. CONCLUSIONS: In this industrial cohort of men, with a relatively low incidence of CHD, smoking and serum cholesterol at baseline were independently associated with the incidence of CHD over 28 years of observation.
Authors: Alejandro Marín; María José Medrano; José González; Héctor Pintado; Vicente Compaired; Mario Bárcena; María Victoria Fustero; Javier Tisaire; José M Cucalón; Aurelio Martín; Raquel Boix; Francisco Hernansanz; José Bueno Journal: BMC Public Health Date: 2006-02-17 Impact factor: 3.295
Authors: Manuel A Gómez-Marcos; Gonzalo Grandes; José A Iglesias-Valiente; Alvaro Sánchez; Imanol Montoya; Luis García-Ortiz Journal: Int J Environ Res Public Health Date: 2009-11-11 Impact factor: 3.390
Authors: Manuel A Gómez-Marcos; Carlos Martínez-Salgado; Carlos Martin-Cantera; José I Recio-Rodríguez; Yolanda Castaño-Sánchez; Maria Giné-Garriga; Emiliano Rodriguez-Sanchez; Luis García-Ortiz Journal: BMC Cardiovasc Disord Date: 2009-05-11 Impact factor: 2.298
Authors: Joan-Josep Cabré; Francisco Martín; Bernardo Costa; Josep L Piñol; Josep L Llor; Yolanda Ortega; Josep Basora; Marta Baldrich; Rosa Solà; Jordi Daniel; Josep Ma Hernández; Judit Saumell; Jordi Bladé; Ramon Sagarra; Teresa Basora; Dolors Montañés; Joan L Frigola; Angel Donado-Mazarrón; Maria Teresa García-Vidal; Isabel Sánchez-Oro; Josep M de Magriñà; Ana Urbaneja; Francisco Barrio; Jesús Vizcaíno; Josep M Sabaté; Irene Pascual; Vanesa Revuelta Journal: BMC Public Health Date: 2008-07-22 Impact factor: 3.295