Literature DB >> 11590549

The importance of genealogy in determining genetic associations with complex traits.

D L Newman, M Abney, M S McPeek, C Ober, N J Cox.   

Abstract

Mesh：

Year:  2001        PMID： 11590549      PMCID： PMC1274359          DOI： 10.1086/323659

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


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  24 in total

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4.  Statistical tests for detection of misspecified relationships by use of genome-screen data.

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8.  beta(2)-adrenergic receptor Arg16/Arg16 genotype is associated with reduced lung function, but not with asthma, in the Hutterites.

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9.  Genetics of asthma: the University of Toronto Program. University of Toronto Genetics of Asthma Research Group.

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Journal:  Am J Respir Crit Care Med       Date:  1997-10       Impact factor: 21.405

Review 10.  Genetic dissection of complex traits.

Authors:  E S Lander; N J Schork
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  35 in total

1.  Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites.

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Review 2.  Identifying genes and genetic variation underlying human diseases and complex phenotypes via recombination mapping.

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3.  Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus.

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4.  Gencrypt: one-way cryptographic hashes to detect overlapping individuals across samples.

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6.  Accounting for relatedness in family based genetic association studies.

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8.  Comparing population structure as inferred from genealogical versus genetic information.

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9.  Variance component model to account for sample structure in genome-wide association studies.

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10.  Genealogical analysis as a new approach for the investigation of drug intolerance heritability.

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