| Literature DB >> 1159007 |
U P Geiger, P H Degen, A Sioufi.
Abstract
Diclofenac and an internal standard are isolated from biological samples by acid-specific extraction and converted into the corresponding indolones with 0.5% sulphuric acid in 2,2,2-trifluorethanol. The neutral derivatives are isolated by solvent extraction and subjected to gas-liquid chromatography. The use of an electron capture detector permits the assay of diclofenac at levels down to 2 ng per sample.Entities:
Mesh：
Substances：
Year: 1975 PMID： 1159007 DOI： 10.1016/s0021-9673(00)99277-x
Source DB: PubMed Journal: J Chromatogr