Literature DB >> 11586289

Islands of linkage disequilibrium.

D B Goldstein.   

Abstract

A detailed knowledge of patterns of linkage disequilibrium in human populations is widely seen as a prerequisite for effective population-based disease gene mapping. New data suggest that linkage disequilibrium is highly structured into discrete blocks of sequence separated by hot spots of recombination.

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Mesh：

Year:  2001        PMID： 11586289     DOI： 10.1038/ng1001-109

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  77 in total

1.  Hierarchical high-throughput SNP genotyping of the human Y chromosome using MALDI-TOF mass spectrometry.

Authors:  Silvia Paracchini; Barbara Arredi; Rod Chalk; Chris Tyler-Smith
Journal:  Nucleic Acids Res       Date:  2002-03-15       Impact factor: 16.971

2.  Genome-wide search for markers associated with bovine spongiform encephalopathy.

Authors:  Jules Hernández-Sánchez; Dave Waddington; Pamela Wiener; Chris S Haley; John L Williams
Journal:  Mamm Genome       Date:  2002-03       Impact factor: 2.957

3.  The first linkage disequilibrium (LD) maps: delineation of hot and cold blocks by diplotype analysis.

Authors:  N Maniatis; A Collins; C F Xu; L C McCarthy; D R Hewett; W Tapper; S Ennis; X Ke; N E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  2002-02-12       Impact factor: 11.205

4.  Randomly distributed crossovers may generate block-like patterns of linkage disequilibrium: an act of genetic drift.

Authors:  Kun Zhang; Joshua M Akey; Ning Wang; Momiao Xiong; Ranajit Chakraborty; Li Jin
Journal:  Hum Genet       Date:  2003-04-03       Impact factor: 4.132

5.  Partition-ligation-expectation-maximization algorithm for haplotype inference with single-nucleotide polymorphisms.

Authors:  Zhaohui S Qin; Tianhua Niu; Jun S Liu
Journal:  Am J Hum Genet       Date:  2002-11       Impact factor: 11.025

6.  Properties of linkage disequilibrium (LD) maps.

Authors:  Weilhua Zhang; Andrew Collins; Nikolas Maniatis; William Tapper; Newton E Morton
Journal:  Proc Natl Acad Sci U S A       Date:  2002-12-16       Impact factor: 11.205

7.  Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation.

Authors:  Ning Wang; Joshua M Akey; Kun Zhang; Ranajit Chakraborty; Li Jin
Journal:  Am J Hum Genet       Date:  2002-10-15       Impact factor: 11.025

Review 8.  On the applicability of a haplotype map to un-assayed populations.

Authors:  Itsik Pe'er; Jacques S Beckmann
Journal:  Hum Genet       Date:  2003-10-25       Impact factor: 4.132

9.  Common 5' beta-globin RFLP haplotypes harbour a surprising level of ancestral sequence mosaicism.

Authors:  Matthew T Webster; John B Clegg; Rosalind M Harding
Journal:  Hum Genet       Date:  2003-05-08       Impact factor: 4.132

10.  Protein kinase C/zeta (PRKCZ) gene is associated with type 2 diabetes in Han population of North China and analysis of its haplotypes.

Authors:  Yun-Feng Li; Hong-Xia Sun; Guo-Dong Wu; Wei-Nan Du; Jin Zuo; Yan Shen; Bo-Qin Qiang; Zhi-Jian Yao; Heng Wang; Wei Huang; Zhu Chen; Mo-Miao Xiong; Yan Meng; Fu-De Fang
Journal:  World J Gastroenterol       Date:  2003-09       Impact factor: 5.742
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