| Literature DB >> 11585674 |
Abstract
The development of mouse models for cystic fibrosis has provided the opportunity to dissect disease pathogenesis, correlate genotype and phenotype, study disease-modifying genes and develop novel therapeutics. This review discusses the successes and the challenges encountered in characterizing and optimizing these models.Entities:
Mesh:
Year: 2001 PMID: 11585674 DOI: 10.1016/s0168-9525(01)02452-0
Source DB: PubMed Journal: Trends Genet ISSN: 0168-9525 Impact factor: 11.639