Literature DB >> 11584304

The renaissance of GSK3.

P Cohen1, S Frame.   

Abstract

Glycogen synthase kinase 3 (GSK3) was initially described as a key enzyme involved in glycogen metabolism, but is now known to regulate a diverse array of cell functions. The study of the substrate specificity and regulation of GSK3 activity has been important in the quest for therapeutic intervention.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11584304     DOI: 10.1038/35096075

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  563 in total

1.  GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α.

Authors:  Daniela Flügel; Agnes Görlach; Thomas Kietzmann
Journal:  Blood       Date:  2011-12-05       Impact factor: 22.113

Review 2.  The integrin-actin connection, an eternal love affair.

Authors:  Cord Brakebusch; Reinhard Fässler
Journal:  EMBO J       Date:  2003-05-15       Impact factor: 11.598

Review 3.  ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions.

Authors:  Philippe P Roux; John Blenis
Journal:  Microbiol Mol Biol Rev       Date:  2004-06       Impact factor: 11.056

4.  Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation.

Authors:  Ambereen Ali; Ji Zhang; Shideng Bao; Irene Liu; Diane Otterness; Nicholas M Dean; Robert T Abraham; Xiao-Fan Wang
Journal:  Genes Dev       Date:  2004-02-01       Impact factor: 11.361

5.  Enhanced antitumorigenic effects in glioblastoma on double targeting of pleiotrophin and its receptor ALK.

Authors:  Marius Grzelinski; Florian Steinberg; Tobias Martens; Frank Czubayko; Katrin Lamszus; Achim Aigner
Journal:  Neoplasia       Date:  2009-02       Impact factor: 5.715

6.  Glycogen synthase kinase-3beta induces neuronal cell death via direct phosphorylation of mixed lineage kinase 3.

Authors:  Rajakishore Mishra; Manoj K Barthwal; Gautam Sondarva; Basabi Rana; Lucas Wong; Malay Chatterjee; James R Woodgett; Ajay Rana
Journal:  J Biol Chem       Date:  2007-08-21       Impact factor: 5.157

Review 7.  Physiological roles of glycogen synthase kinase-3: potential as a therapeutic target for diabetes and other disorders.

Authors:  J R Woodgett
Journal:  Curr Drug Targets Immune Endocr Metabol Disord       Date:  2003-12

8.  Identification of glycogen synthase as a new substrate for stress-activated protein kinase 2b/p38beta.

Authors:  Yvonne Kuma; David G Campbell; Ana Cuenda
Journal:  Biochem J       Date:  2004-04-01       Impact factor: 3.857

9.  Crosstalk between phosphodiesterase 7 and glycogen synthase kinase-3: two relevant therapeutic targets for neurological disorders.

Authors:  Jose A Morales-Garcia; Valle Palomo; Miriam Redondo; Sandra Alonso-Gil; Carmen Gil; Ana Martinez; Ana Perez-Castillo
Journal:  ACS Chem Neurosci       Date:  2014-01-17       Impact factor: 4.418

10.  8-bromo-7-methoxychrysin inhibits properties of liver cancer stem cells via downregulation of β-catenin.

Authors:  Mei-Fang Quan; Li-Hong Xiao; Zhi-Hong Liu; Hui Guo; Kai-Qun Ren; Fei Liu; Jian-Guo Cao; Xi-Yun Deng
Journal:  World J Gastroenterol       Date:  2013       Impact factor: 5.742

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.