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Literature DB >> 12743027

The integrin-actin connection, an eternal love affair.

Abstract

Integrin receptors connect the extracellular matrix to the actin cytoskeleton. This interaction can be viewed as a cyclical liaison, which develops again and again at new adhesion sites only to cease at sites of de-adhesion. Recent work has demonstrated that multidomain proteins play crucial roles in the integrin-actin connection by providing a high degree of regulation adjusted to the needs of the cell. In this review we present several examples of this paradigm and with special emphasis on the ILK-PINCH-parvin complex, which amply demonstrates how structural and signalling functions are linked together.

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Year: 2003 PMID： 12743027 PMCID： PMC156003 DOI： 10.1093/emboj/cdg245

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

116 in total

Review 1. Integrins in invasive growth.

Authors: Cord Brakebusch; Daniel Bouvard; Fabio Stanchi; Takao Sakai; Reinhard Fässler
Journal: J Clin Invest Date: 2002-04 Impact factor: 14.808

2. Integrins regulate GTP-Rac localized effector interactions through dissociation of Rho-GDI.

Authors: Miguel Angel Del Pozo; William B Kiosses; Nazilla B Alderson; Nahum Meller; Klaus M Hahn; Martin Alexander Schwartz
Journal: Nat Cell Biol Date: 2002-03 Impact factor: 28.824

3. A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face.

Authors: Olga Vinogradova; Algirdas Velyvis; Asta Velyviene; Bin Hu; Thomas Haas; Edward Plow; Jun Qin
Journal: Cell Date: 2002-09-06 Impact factor: 41.582

Review 4. Integrins: bidirectional, allosteric signaling machines.

Authors: Richard O Hynes
Journal: Cell Date: 2002-09-20 Impact factor: 41.582

5. Dissecting the link between stress fibres and focal adhesions by CALI with EGFP fusion proteins.

Authors: Zenon Rajfur; Partha Roy; Carol Otey; Lewis Romer; Ken Jacobson
Journal: Nat Cell Biol Date: 2002-04 Impact factor: 28.824

6. C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes.

Authors: A Craig Mackinnon; Hiroshi Qadota; Kenneth R Norman; Donald G Moerman; Benjamin D Williams
Journal: Curr Biol Date: 2002-05-14 Impact factor: 10.834

7. Identification of a plasma membrane Raft-associated PKB Ser473 kinase activity that is distinct from ILK and PDK1.

Authors: Michelle M Hill; Jianhua Feng; Brian A Hemmings
Journal: Curr Biol Date: 2002-07-23 Impact factor: 10.834

8. Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1.

Authors: Ratna K Vadlamudi; Feng Li; Liana Adam; Diep Nguyen; Yasutaka Ohta; Thomas P Stossel; Rakesh Kumar
Journal: Nat Cell Biol Date: 2002-09 Impact factor: 28.824

9. A crucial role of beta 1 integrins for keratinocyte migration in vitro and during cutaneous wound repair.

Authors: Richard Grose; Caroline Hutter; Wilhelm Bloch; Irmgard Thorey; Fiona M Watt; Reinhard Fässler; Cord Brakebusch; Sabine Werner
Journal: Development Date: 2002-05 Impact factor: 6.868

10. Matrix assembly, regulation, and survival functions of laminin and its receptors in embryonic stem cell differentiation.

Authors: Shaohua Li; David Harrison; Salvatore Carbonetto; Reinhard Fassler; Neil Smyth; David Edgar; Peter D Yurchenco
Journal: J Cell Biol Date: 2002-06-24 Impact factor: 10.539

135 in total

Review 1. Neurogenic astrocytes and their glycoconjugates: not just "glue" anymore.

Authors: Dennis A Steindler
Journal: Methods Mol Biol Date: 2012

2. Dexamethasone-associated cross-linked actin network formation in human trabecular meshwork cells involves β3 integrin signaling.

Authors: Mark S Filla; Marie K Schwinn; Amanda K Nosie; Ross W Clark; Donna M Peters
Journal: Invest Ophthalmol Vis Sci Date: 2011-05-05 Impact factor: 4.799

3. Beta1 and beta3 integrins cooperate to induce syndecan-4-containing cross-linked actin networks in human trabecular meshwork cells.

Authors: Mark S Filla; Anne Woods; Paul L Kaufman; Donna M Peters
Journal: Invest Ophthalmol Vis Sci Date: 2006-05 Impact factor: 4.799

Review 4. Apoptosis regulation in the mammary gland.

Authors: K A Green; C H Streuli
Journal: Cell Mol Life Sci Date: 2004-08 Impact factor: 9.261

Review 5. Integrin signaling and mammary cell function.

Authors: Franziska Schatzmann; Rebecca Marlow; Charles H Streuli
Journal: J Mammary Gland Biol Neoplasia Date: 2003-10 Impact factor: 2.673

Review 6. Breaching multiple barriers: leukocyte motility through venular walls and the interstitium.

Authors: Sussan Nourshargh; Peter L Hordijk; Michael Sixt
Journal: Nat Rev Mol Cell Biol Date: 2010-05 Impact factor: 94.444

7. A role for beta-actin in RNA polymerase III transcription.

Authors: Ping Hu; Si Wu; Nouria Hernandez
Journal: Genes Dev Date: 2004-12-01 Impact factor: 11.361

8. p38 mitogen-activated protein kinase interacts with vinculin at focal adhesions during fatty acid-stimulated cell adhesion.

Authors: Margaret D George; Robert N Wine; Brad Lackford; Grace E Kissling; Steven K Akiyama; Kenneth Olden; John D Roberts
Journal: Biochem Cell Biol Date: 2013-06-24 Impact factor: 3.626

Review 9. Podocyte-actin dynamics in health and disease.

Authors: Luca Perico; Sara Conti; Ariela Benigni; Giuseppe Remuzzi
Journal: Nat Rev Nephrol Date: 2016-08-30 Impact factor: 28.314

10. Modulation of host cell mechanics by Trypanosoma cruzi.

Authors: Adam Mott; Guillaume Lenormand; Jaime Costales; Jeffrey J Fredberg; Barbara A Burleigh
Journal: J Cell Physiol Date: 2009-02 Impact factor: 6.384