Literature DB >> 11578923

Adenosylmethionine as a source of 5'-deoxyadenosyl radicals.

M Fontecave1, E Mulliez, S Ollagnier-de-Choudens.   

Abstract

The combination of an iron-sulfur cluster and S-adenosylmethionine provides a novel mechanism for the initiation of radical catalysis in an unanticipated variety of metabolic processes. Molecular details of the cluster-mediated reductive cleavage of S-adenosylmethionine to methionine and, presumably, a 5'-deoxyadenosyl radical are the targets of recent studies.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11578923     DOI： 10.1016/s1367-5931(00)00237-4

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  28 in total

1.  Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes.

Authors:  Gunhild Layer; Jürgen Moser; Dirk W Heinz; Dieter Jahn; Wolf-Dieter Schubert
Journal:  EMBO J       Date:  2003-12-01       Impact factor: 11.598

2.  Evidence from Mössbauer spectroscopy for distinct [2Fe-2S](2+) and [4Fe-4S](2+) cluster binding sites in biotin synthase from Escherichia coli.

Authors:  Natalia B Ugulava; Kristene K Surerus; Joseph T Jarrett
Journal:  J Am Chem Soc       Date:  2002-08-07       Impact factor: 15.419

3.  Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.

Authors:  Akiko Noma; Yohei Kirino; Yoshiho Ikeuchi; Tsutomu Suzuki
Journal:  EMBO J       Date:  2006-04-27       Impact factor: 11.598

4.  DNA repair and free radicals, new insights into the mechanism of spore photoproduct lyase revealed by single amino acid substitution.

Authors:  Alexia Chandor-Proust; Olivier Berteau; Thierry Douki; Didier Gasparutto; Sandrine Ollagnier-de-Choudens; Marc Fontecave; Mohamed Atta
Journal:  J Biol Chem       Date:  2008-10-27       Impact factor: 5.157

5.  RNA methylation by radical SAM enzymes RlmN and Cfr proceeds via methylene transfer and hydride shift.

Authors:  Feng Yan; Danica Galonic Fujimori
Journal:  Proc Natl Acad Sci U S A       Date:  2011-02-22       Impact factor: 11.205

6.  Viperin: a radical response to viral infection.

Authors:  Kaitlin S Duschene; Joan B Broderick
Journal:  Biomol Concepts       Date:  2012-06

7.  Post-translational modification of ribosomal proteins: structural and functional characterization of RimO from Thermotoga maritima, a radical S-adenosylmethionine methylthiotransferase.

Authors:  Simon Arragain; Ricardo Garcia-Serres; Geneviève Blondin; Thierry Douki; Martin Clemancey; Jean-Marc Latour; Farhad Forouhar; Helen Neely; Gaetano T Montelione; John F Hunt; Etienne Mulliez; Marc Fontecave; Mohamed Atta
Journal:  J Biol Chem       Date:  2009-12-09       Impact factor: 5.157

Review 8.  Anaerobic functionalization of unactivated C-H bonds.

Authors:  Squire J Booker
Journal:  Curr Opin Chem Biol       Date:  2009-03-16       Impact factor: 8.822

9.  Inactivation of E. coli pyruvate formate-lyase: role of AdhE and small molecules.

Authors:  Mbako R Nnyepi; Yi Peng; Joan B Broderick
Journal:  Arch Biochem Biophys       Date:  2007-01-12       Impact factor: 4.013

10.  Further characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in the mechanism of catalysis.

Authors:  Tyler L Grove; Jessica H Ahlum; Rosie M Qin; Nicholas D Lanz; Matthew I Radle; Carsten Krebs; Squire J Booker
Journal:  Biochemistry       Date:  2013-04-16       Impact factor: 3.162
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.