| Literature DB >> 11572773 |
Abstract
This review describes the structure of telomeres, the protective DNA-protein complexes at eukaryotic chromosomal ends, and several molecular mechanisms involved in telomere functions. Also discussed are cellular responses to compromising the functions of telomeres and of telomerase, which synthesizes telomeric DNA.Mesh:
Substances:
Year: 2001 PMID: 11572773 DOI: 10.1016/s0092-8674(01)00492-5
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582