Literature DB >> 1157030

Intracavitary irradiation of early rectal cancer for cure. A series of 186 cases.

J Papillon.   

Abstract

If radical surgery is the only rational policy for most cases of rectal cancer, the problem of local treatment in poor surgical risk patients should be discussed in selected cases. Only limited, fairly-well-differentiated tumors, still confined to the rectal wall may have a sufficiently low probability of lymphatic spread to be amenable to local treatment. Rectal cancer, usually regarded as being slightly radiosensitive when treated by external irradiation, proves to be highly radiosensitive in the case of early cancer treated by intracavitary irradiation. This method is able to control a large amount of limited polypoid and ulcerative adenocarcinomas. In a series of 133 cases followed more than 5 years, the rate of death from cancer is only 9%, and the 5-year survival rate is 78%. As compared with local exision or electrocoagulation, intracavitary irradiation has several advantages. It does not require colostomy nor anesthesia. Contact x-ray therapy is an ambulatory treatment applicable even to elderly and fragile patients. There is no danger of fistula in the case of tumor of the anterior wall in female patients. It preserves all the chances of cure by subsequent surgery in case of failure.

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Year:  1975        PMID: 1157030     DOI: 10.1002/1097-0142(197508)36:2+<696::aid-cncr2820360813>3.0.co;2-x

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  16 in total

Review 1.  Anastomosis or stoma for low rectal cancer?

Authors:  C Hall; S Rowley; J P Neoptolemos
Journal:  Postgrad Med J       Date:  1989-03       Impact factor: 2.401

2.  Advanced rectal cancer.

Authors: 
Journal:  BMJ       Date:  1990-03-03

Review 3.  Electrocoagulation for adenocarcinoma of the low rectum.

Authors:  T E Eisenstat; G C Oliver
Journal:  World J Surg       Date:  1992 May-Jun       Impact factor: 3.352

Review 4.  Colorectal cancer.

Authors:  L D Leffall
Journal:  J Natl Med Assoc       Date:  1985-04       Impact factor: 1.798

Review 5.  Radiotherapy in management of gastrointestinal carcinoma: a review.

Authors:  R D James
Journal:  J R Soc Med       Date:  1980-09       Impact factor: 5.344

6.  Radiation therapy of rectal cancer.

Authors:  A M Cohen; L L Gunderson; C E Welch
Journal:  World J Surg       Date:  1982-09       Impact factor: 3.352

Review 7.  Management of locally advanced rectal cancer in the elderly: a critical review and algorithm.

Authors:  Lara Hathout; Nell Maloney-Patel; Usha Malhotra; Shang-Jui Wang; Sita Chokhavatia; Ishita Dalal; Elizabeth Poplin; Salma K Jabbour
Journal:  J Gastrointest Oncol       Date:  2018-04

8.  Adjuvant postoperative radiation therapy for Dukes C adenocarcinoma of the rectum.

Authors:  S A Localio; W Nealon; J Newall; Q Valensi
Journal:  Ann Surg       Date:  1983-07       Impact factor: 12.969

9.  CT staging of early rectal carcinoma.

Authors:  J H Göthlin; R M Lerner; G Gadeholt; B Sischy; J Hinson
Journal:  Gastrointest Radiol       Date:  1987

10.  Carcinoma of the rectum and rectosigmoid colon: role of radiation therapy.

Authors:  E K Reddy; C M Mansfield; G V Hartman
Journal:  J Natl Med Assoc       Date:  1978-11       Impact factor: 1.798

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