Literature DB >> 11567944

Severe upper airway obstruction caused by ulcerative laryngitis.

M Hatherill1, L Reynolds, Z Waggie, A Argent.   

Abstract

AIMS: To present our experience of severe upper airway obstruction caused by ulcerative laryngitis in children.
METHODS: Retrospective case note review of 263 children with severe upper airway obstruction and a clinical diagnosis of croup admitted to a paediatric intensive care unit (PICU) over a five year period.
RESULTS: A total of 148 children (56%) underwent microlaryngoscopy (Storz 3.0 rigid telescope). Laryngeal ulceration with oedema was documented in 15 of these children (10%), median age 14 months (range 10-36) and median weight 10 kg (range 6-12). Twenty seven of the children who underwent microlaryngoscopy (18%) also had ulcerative gingivostomatitis consistent with herpes simplex virus infection. Ulcerative laryngitis was documented in nine of 27 (33%) children with, and in six of 121 (5%) children without, coexistent ulcerative gingivostomatitis. One of the 15 children did not require airway intervention. Nine children required nasotracheal intubation for a median of 4 days (range 3-11) and median PICU stay of 6 days (range 4-14). Five children required tracheostomy ab initio, with a median PICU stay of 30 days (range 20-36), and duration of tracheostomy in situ for a median of 19 days (range 15-253). All 15 children survived.
CONCLUSION: Ulcerative laryngitis is more common in our patient population than the few reports suggest. Early diagnostic microlaryngoscopy is recommended in children with severe croup who follow an atypical course.

Entities:  

Mesh:

Year:  2001        PMID: 11567944      PMCID: PMC1718954          DOI: 10.1136/adc.85.4.326

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  8 in total

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Authors:  M Y Mancao; L J Sindel; P H Richardson; F M Silver
Journal:  Acta Paediatr       Date:  1996-01       Impact factor: 2.299

2.  The treatment of croup with glucocorticoids.

Authors:  D M Jaffe
Journal:  N Engl J Med       Date:  1998-08-20       Impact factor: 91.245

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Journal:  Pediatr Pathol       Date:  1989

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Authors:  S Bogger-Goren
Journal:  Pediatr Infect Dis J       Date:  1987-12       Impact factor: 2.129

5.  A comparison of nebulized budesonide, intramuscular dexamethasone, and placebo for moderately severe croup.

Authors:  D W Johnson; S Jacobson; P C Edney; P Hadfield; M E Mundy; S Schuh
Journal:  N Engl J Med       Date:  1998-08-20       Impact factor: 91.245

6.  Fatal lower respiratory tract infection due to herpes simplex virus in a previously healthy child.

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Journal:  Clin Pediatr (Phila)       Date:  1984-07       Impact factor: 1.168

7.  Herpes simplex virus infection. A rare cause of prolonged croup.

Authors:  A F Inglis
Journal:  Arch Otolaryngol Head Neck Surg       Date:  1993-05

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Authors:  J B Harris; R Lusk; J S Wagener; R D Andersen
Journal:  Otolaryngol Head Neck Surg       Date:  1987-02       Impact factor: 3.497

  8 in total
  2 in total

1.  A case of atypical croup.

Authors:  Geoff Cuvelier; Amged El-Hawrani; Hamdy El-Hakim; Joan L Robinson
Journal:  Can J Infect Dis Med Microbiol       Date:  2005-11       Impact factor: 2.471

2.  Defining atypical croup: A case report and review of the literature.

Authors:  Raphael Hanna; Francisco Lee; Derek Drummond; Warren K Yunker
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2019-09-17       Impact factor: 1.675

  2 in total

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