Literature DB >> 1156788

Urinary N-acetyl- beta-D-glucosaminidase activities in patients with renal disease.

J M Wellwood, B G Ellis, R G Price, K Hammond, A E Thompson, N F Jones.   

Abstract

Urinary N-acetyl-beta-D-glucosaminidase (NAG) activities were assayed in every urine void throughout 24 hours in 17 normal people and in four patients with renal disease. The variation in NAG activity due to changing rates of urine flow was almost eliminated by factoring enzyme activity by the urinary creatinine concentration. Random samples of urine may thus be used for assay. The results of NAG assay in 36 patients with acute and chronic renal diseases showed that NAG was a sensitive indicator of renal damage. This simple test may be valuable in detecting or monitoring renal disease.

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Year:  1975        PMID: 1156788      PMCID: PMC1673872          DOI: 10.1136/bmj.3.5980.408

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  6 in total

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Authors:  S B ROSALKI; J H WILKINSON
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Authors:  R Sandman; R M Margules; S L Kountz
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Journal:  Scand J Clin Lab Invest       Date:  1972-10       Impact factor: 1.713

6.  Early warning of rejection?

Authors:  J M Wellwood; B G Ellis; J H Hall; D R Robinson; A E Thompson
Journal:  Br Med J       Date:  1973-05-05
  6 in total
  44 in total

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Authors:  R J Pierce; R G Price; J S Fowler
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4.  N-acetyl-B-D-glucosaminidase isoenzymes in the diagnosis of poisoning and kidney diseases.

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Authors:  P K Buamah; A Howell; H Whitby; E S Harpur; A Gescher
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6.  Gentamicin and sisomicin - induced renal tubular damage.

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8.  Changes in the urinary excretion of creatinine, albumin and N-acetyl-beta-D-glucosaminidase with increasing age and maturity in healthy schoolchildren.

Authors:  A M Skinner; G M Addison; D A Price
Journal:  Eur J Pediatr       Date:  1996-07       Impact factor: 3.183

9.  Comparative analysis of urinary biomarkers for early detection of acute kidney injury following cardiopulmonary bypass.

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10.  Cardio-renal syndromes: report from the consensus conference of the acute dialysis quality initiative.

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Journal:  Eur Heart J       Date:  2009-12-25       Impact factor: 29.983

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