Literature DB >> 1156524

Biosynthesis of 17beta-oestradiol in human breast carcinoma tissue and a novel method for its characterization.

J B Adams, K Li.   

Abstract

Conversion of 7alpha3H-testosterone to 17beta-oestradiol by human mammary carcinoma tissue in vitro has been demonstrated. It was characterized unequivocally by conversion to 17beta-oestradiol-3-sulphate upon incubation with adenosine-3'-phosphate-5'-phosphosulphate and the highly specific enzyme oestrogen sulphotransferase.

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Year:  1975        PMID： 1156524      PMCID： PMC2009460          DOI： 10.1038/bjc.1975.82

Source DB:  PubMed          Journal:  Br J Cancer        ISSN： 0007-0920            Impact factor:   7.640


  7 in total

1.  The enzymic synthesis of the sulfate esters of estradiol-17beta and diethylstilbesterol.

Authors:  A H PAYNE; M MASON
Journal:  Biochim Biophys Acta       Date:  1963-06-04

2.  Conjugation of steroid hormones by normal and neoplastic tissues.

Authors:  T L Dao; P R Libby
Journal:  J Clin Endocrinol Metab       Date:  1968-10       Impact factor: 5.958

3.  Enzymic synthesis of steroid sulphates. X. Isolation of oestrogen sulphotransferase from bovine placenta and comparison of its properties with adrenal oestrogen sulphotransferase.

Authors:  J B Adams; J Low
Journal:  Biochim Biophys Acta       Date:  1974-11-25

4.  Oestradiol synthesis by a human breast carcinoma.

Authors:  W R Miller; A P Forrest
Journal:  Lancet       Date:  1974-10-12       Impact factor: 79.321

5.  Steroid metabolism by human breast tumours.

Authors:  D Jones; E H Cameron; K Griffiths; E N Gleave; A P Forrest
Journal:  Biochem J       Date:  1970-03       Impact factor: 3.857

6.  Specificity studies on bovine adrenal estrogen sulfotransferase.

Authors:  J Rozhin; R L Soderstrom; S C Brooks
Journal:  J Biol Chem       Date:  1974-04-10       Impact factor: 5.157

7.  Enzymic synthesis of steroid sulphates. 3. Isolation and properties of estrogen sulphotransferase of bovine adrenal glands.

Authors:  J B Adams; A Poulos
Journal:  Biochim Biophys Acta       Date:  1967
  7 in total
  9 in total

1.  Aromatase in breast cancer tissue--localization and relationship with reproductive status of patients.

Authors:  L M Berstein; A A Larionov; A Sh Kyshtoobaeva; K M Pozharisski; V F Semiglazov; O A Ivanova
Journal:  J Cancer Res Clin Oncol       Date:  1996       Impact factor: 4.553

2.  An aroma of complexity: how the unique genetics of aromatase (CYP19A1) explain diverse phenotypes from hens and hyenas to human gynecomastia, and testicular and other tumors.

Authors:  Constantine A Stratakis
Journal:  J Clin Endocrinol Metab       Date:  2013-12       Impact factor: 5.958

Review 3.  Modulation of estrogen synthesis and metabolism by phytoestrogens in vitro and the implications for women's health.

Authors:  Majorie B M van Duursen
Journal:  Toxicol Res (Camb)       Date:  2017-09-08       Impact factor: 3.524

4.  Tumour steroid hormone synthesis and estrogen receptor status in breast cancer patients.

Authors:  R C Mason; D A Burns; W R Miller; R A Hawkins; A P Forrest
Journal:  Breast Cancer Res Treat       Date:  1981       Impact factor: 4.872

Review 5.  Suppression of estrogens with aminoglutethimide and hydrocortisone (medical adrenalectomy) as treatment of advanced breast carcinoma: a review.

Authors:  R J Santen
Journal:  Breast Cancer Res Treat       Date:  1981       Impact factor: 4.872

6.  Adrenal steroids stimulate growth and progesterone receptor levels in rat uterus and DMBA-induced mammary tumors.

Authors:  P G Spinola; B Marchetti; F Labrie
Journal:  Breast Cancer Res Treat       Date:  1986       Impact factor: 4.872

7.  Estrone sulfate: a potential source of estradiol in human breast cancer tissues.

Authors:  S J Santner; D Leszczynski; C Wright; A Manni; P D Feil; R J Santen
Journal:  Breast Cancer Res Treat       Date:  1986       Impact factor: 4.872

8.  The relationship of urinary and plasma androgens to steroid receptors and menopausal status in breast cancer patients and their influence on survival.

Authors:  B H Mason; I M Holdaway; S J Skinner; R G Kay
Journal:  Breast Cancer Res Treat       Date:  1994       Impact factor: 4.872

9.  Human breast tumour cytosol oestrogen receptor binding to oligo(dT)-cellulose.

Authors:  L Myatt; J O White; M D Fernandez; J I Burn
Journal:  Br J Cancer       Date:  1982-06       Impact factor: 7.640
  9 in total

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