Literature DB >> 11563757

Application of large-eddy simulation to the study of pulsatile flow in a modeled arterial stenosis.

R Mittal1, S P Simmons, H S Udaykumar.   

Abstract

The technique of large-eddy simulation (LES) has been applied to the study of pulsatile flow through a modeled arterial stenosis. A simple stenosis model has been used that consists of a one-sided 50 percent semicircular constriction in a planar channel. The inlet volume flux is varied sinusoidally in time in a manner similar to the laminar flow simulations of Tutty (1992). LES is used to compute flow at a peak Reynolds number of 2000 and a Strouhal number of 0.024. At this Reynolds number, the flow downstream of the stenosis transitions to turbulence and exhibits all the classic features of post-stenotic flow as described by Khalifa and Giddens (1981) and Lieber and Giddens (1990). These include the periodic shedding of shear layer vortices and transition to turbulence downstream of the stenosis. Computed frequency spectra indicate that the vortex shedding occurs at a distinct high frequency, and the potential implication of this for noninvasive diagnosis of arterial stenoses is discussed. A variety of statistics have been also extracted and a number of other physical features of the flow are described in order to demonstrate the usefulness of LES for the study of post-stenotic flows.

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Year:  2001        PMID: 11563757     DOI: 10.1115/1.1385840

Source DB:  PubMed          Journal:  J Biomech Eng        ISSN: 0148-0731            Impact factor:   2.097


  19 in total

1.  Arterial geometry, flow pattern, wall shear and mass transport: potential physiological significance.

Authors:  G Coppola; C Caro
Journal:  J R Soc Interface       Date:  2008-11-25       Impact factor: 4.118

2.  Large eddy simulation of transitional flow in an idealized stenotic blood vessel: evaluation of subgrid scale models.

Authors:  Abhro Pal; Kameswararao Anupindi; Yann Delorme; Niranjan Ghaisas; Dinesh A Shetty; Steven H Frankel
Journal:  J Biomech Eng       Date:  2014-07       Impact factor: 2.097

3.  Effect of stenosis shape on the sound emitted from a constricted blood vessel.

Authors:  Kamil Ozden; Cuneyt Sert; Yigit Yazicioglu
Journal:  Med Biol Eng Comput       Date:  2020-01-14       Impact factor: 2.602

4.  Dependence of leukocyte capture on instantaneous pulsatile flow.

Authors:  Umberto Ciri; Rita Bhui; Jorge Bailon-Cuba; Heather N Hayenga; Stefano Leonardi
Journal:  J Biomech       Date:  2018-06-15       Impact factor: 2.712

5.  Multiblock High Order Large Eddy Simulation of Powered Fontan Hemodynamics: Towards Computational Surgery.

Authors:  Yann T Delorme; Mark D Rodefeld; Steven H Frankel
Journal:  Comput Fluids       Date:  2016-11-09       Impact factor: 3.013

6.  Isolating the Effect of Arch Architecture on Aortic Hemodynamics Late After Coarctation Repair: A Computational Study.

Authors:  Vahid Goodarzi Ardakani; Harshinee Goordoyal; Maria Victoria Ordonez; Froso Sophocleous; Stephanie Curtis; Radwa Bedair; Massimo Caputo; Alberto Gambaruto; Giovanni Biglino
Journal:  Front Cardiovasc Med       Date:  2022-06-24

7.  In vivo measurement of blood flow in a micro-scale stenosis model generated by laser photothermal blood coagulation.

Authors:  Sang Joon Lee; Ho Jin Ha
Journal:  IET Syst Biol       Date:  2013-04       Impact factor: 1.615

8.  Toward a simulation-based tool for the treatment of vocal fold paralysis.

Authors:  Rajat Mittal; Xudong Zheng; Rajneesh Bhardwaj; Jung Hee Seo; Qian Xue; Steven Bielamowicz
Journal:  Front Physiol       Date:  2011-05-02       Impact factor: 4.566

9.  Dynamics of Blood Flows in Aortic Stenosis: Mild, Moderate, and Severe.

Authors:  Choon-Sik Jhun; Raymond Newswanger; Joshua P Cysyk; Sailahari Ponnaluri; Bryan Good; Keefe B Manning; Gerson Rosenberg
Journal:  ASAIO J       Date:  2021-06-01       Impact factor: 3.826

10.  Assessment with clinical data of a coupled bio-hemodynamics numerical model to predict leukocyte adhesion in coronary arteries.

Authors:  Umberto Ciri; Ruth L Bennett; Rita Bhui; David S Molony; Habib Samady; Clark A Meyer; Heather N Hayenga; Stefano Leonardi
Journal:  Sci Rep       Date:  2021-06-16       Impact factor: 4.379

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