Literature DB >> 1156359

The synthesis of hyaluronic acid by sheep and rabbit articular cartilage in vitro.

G C Gillard, B Caterson, D A Lowther.   

Abstract

Standard methods of glycosaminoglycan separation were used to confirm the presence of hyaluronic acid in sheep and rabbit articular cartilage. During incubation of carilage in vitro in the presence of [1-14 C]acetate, cartilage cells synthesize this macromolecule and, under the conditions used, it appears to have a shorter turnover time than chondroitin suplhate in the same tissue. The possible functions of hyaluronic acid in cartilage are discussed.

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Year:  1975        PMID: 1156359      PMCID: PMC1165209          DOI: 10.1042/bj1450209

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  13 in total

1.  A modified uronic acid carbazole reaction.

Authors:  T BITTER; H M MUIR
Journal:  Anal Biochem       Date:  1962-10       Impact factor: 3.365

2.  Effect of leukocyte and synovial membrane extracts on cartilage mucoprotein.

Authors:  M ZIFF; H J GRIBETZ; J LOSPALLUTO
Journal:  J Clin Invest       Date:  1960-02       Impact factor: 14.808

3.  The properties of papain.

Authors:  J R KIMMEL; E L SMITH
Journal:  Adv Enzymol Relat Subj Biochem       Date:  1957

4.  Effect of D-glucosamine concentration on the kinetics of mucopolysaccharide biosynthesis in cultured chick embryo vertebral cartilage.

Authors:  J J Kim; H E Conrad
Journal:  J Biol Chem       Date:  1974-05-25       Impact factor: 5.157

5.  The alkaline cleavage and borohydride reduction of cartilage proteoglycan.

Authors:  H C Robinson; J J Hopwood
Journal:  Biochem J       Date:  1973-07       Impact factor: 3.857

6.  Fractionation and recovery of secretions of synovial cells synthesized in culture with radioactive precursors.

Authors:  E Baxter; J R Fraser; G S Harris
Journal:  Ann Rheum Dis       Date:  1973-01       Impact factor: 19.103

7.  The specific interaction of hyaluronic acid with cartillage proteoglycans.

Authors:  T E Hardingham; H Muir
Journal:  Biochim Biophys Acta       Date:  1972-09-15

8.  Multiple aggregation factors in cartilage proteoglycan.

Authors:  J D Gregory
Journal:  Biochem J       Date:  1973-06       Impact factor: 3.857

9.  Hyaluronic acid in synovial fluid. 3. Effect of maturation and aging on the chemical properties of bovine synovial fluid of different joints.

Authors:  P O Seppälä; E A Balazs
Journal:  J Gerontol       Date:  1969-07

10.  Fine structure and glycosaminoglycan content of the surface layer of articular cartilage.

Authors:  E A Balazs; G A Bloom; D A Swann
Journal:  Fed Proc       Date:  1966 Nov-Dec
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  3 in total

1.  The proteoglycan content and the axial periodicity of collagen in tendon.

Authors:  G C Gillard; M J Merrilees; P G Bell-Booth; H C Reilly; M H Flint
Journal:  Biochem J       Date:  1977-04-01       Impact factor: 3.857

2.  Synthesis of hyaluronate in cultured bovine articular cartilage.

Authors:  C K Ng; C J Handley; R M Mason; H C Robinson
Journal:  Biochem J       Date:  1989-11-01       Impact factor: 3.857

3.  Biosynthesis of proteoglycan in vitro by cartilage from human osteochondrophytic spurs.

Authors:  C J Malemud; V M Goldberg; R W Moskowitz; L L Getzy; R S Papay; D P Norby
Journal:  Biochem J       Date:  1982-08-15       Impact factor: 3.857

  3 in total

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