OBJECTIVE: To evaluate the efficacy of carbidopa L-dopa (Sinemet) in reducing left spatial neglect after stroke. DESIGN: Case series. SETTING: Inpatient neurorehabilitation unit in a regional rehabilitation center. PARTICIPANTS: A convenience sample of 4 women with right brain strokes and left neglect. INTERVENTION: A trial of carbidopa L-dopa to treat left neglect, if indicated by selected subtests of the Behavioral Inattention Test (BIT). MAIN OUTCOME MEASURES: Baseline and posttreatment evaluation with the modified BIT and the FIM instrument. RESULTS: Three of 4 subjects had significant improvements in their modified BIT scores (8%, 12%, 27%, respectively) and their functional status on the FIM. CONCLUSION: With further study, carbidopa L-dopa may be shown to reduce unilateral spatial neglect and thereby improve rehabilitation outcomes.
OBJECTIVE: To evaluate the efficacy of carbidopa L-dopa (Sinemet) in reducing left spatial neglect after stroke. DESIGN: Case series. SETTING: Inpatient neurorehabilitation unit in a regional rehabilitation center. PARTICIPANTS: A convenience sample of 4 women with right brain strokes and left neglect. INTERVENTION: A trial of carbidopa L-dopa to treat left neglect, if indicated by selected subtests of the Behavioral Inattention Test (BIT). MAIN OUTCOME MEASURES: Baseline and posttreatment evaluation with the modified BIT and the FIM instrument. RESULTS: Three of 4 subjects had significant improvements in their modified BIT scores (8%, 12%, 27%, respectively) and their functional status on the FIM. CONCLUSION: With further study, carbidopa L-dopa may be shown to reduce unilateral spatial neglect and thereby improve rehabilitation outcomes.
Authors: Gustavo José Luvizutto; Rodrigo Bazan; Gabriel Pereira Braga; Luiz Antônio de Lima Resende; Silméia Garcia Z Bazan; Regina El Dib Journal: Cochrane Database Syst Rev Date: 2015-11-06
Authors: Nikos Gorgoraptis; Yee-Haur Mah; Bjoern Machner; Victoria Singh-Curry; Paresh Malhotra; Maria Hadji-Michael; David Cohen; Robert Simister; Ajoy Nair; Elena Kulinskaya; Nick Ward; Richard Greenwood; Masud Husain Journal: Brain Date: 2012-07-02 Impact factor: 13.501
Authors: Duc A Tran; Marta Pajaro-Blazquez; Jean-Francois Daneault; Jaime G Gallegos; Jose Pons; Felipe Fregni; Paolo Bonato; Ross Zafonte Journal: Am J Phys Med Rehabil Date: 2016-06 Impact factor: 2.159