Literature DB >> 11543508

Prebiotic synthesis of adenine and amino acids under Europa-like conditions.

M Levy1, S L Miller, K Brinton, J L Bada.   

Abstract

In order to simulate prebiotic synthetic processes on Europa and other ice-covered planets and satellites, we have investigated the prebiotic synthesis of organic compounds from dilute solutions of NH4CN frozen for 25 years at -20 and -78 degrees C. In addition, the aqueous products of spark discharge reactions from a reducing atmosphere were frozen for 5 years at -20 degrees C. We find that both adenine and guanine, as well as a simple set of amino acids dominated by glycine, are produced in substantial yields under these conditions. These results indicate that some of the key components necessary for the origin of life may have been available on Europa throughout its history and suggest that the circumstellar zone where life might arise may be wider than previously thought.

Entities:  

Keywords:  NASA Discipline Exobiology; Non-NASA Center

Mesh:

Substances:

Year:  2000        PMID: 11543508     DOI: 10.1006/icar.2000.6365

Source DB:  PubMed          Journal:  Icarus        ISSN: 0019-1035            Impact factor:   3.508


  26 in total

Review 1.  State-of-the-art instruments for detecting extraterrestrial life.

Authors:  J L Bada
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-30       Impact factor: 11.205

2.  Differential adsorption of nucleic acid bases: Relevance to the origin of life.

Authors:  S J Sowerby; C A Cohn; W M Heckl; N G Holm
Journal:  Proc Natl Acad Sci U S A       Date:  2001-01-30       Impact factor: 11.205

3.  Primordial coding of amino acids by adsorbed purine bases.

Authors:  Stephen J Sowerby; George B Petersen; Nils G Holm
Journal:  Orig Life Evol Biosph       Date:  2002-02       Impact factor: 1.950

4.  The cold origin of life: B. Implications based on pyrimidines and purines produced from frozen ammonium cyanide solutions.

Authors:  Shin Miyakawa; H James Cleaves; Stanley L Miller
Journal:  Orig Life Evol Biosph       Date:  2002-06       Impact factor: 1.950

5.  Inversion concept of the origin of life.

Authors:  V N Kompanichenko
Journal:  Orig Life Evol Biosph       Date:  2012-05-29       Impact factor: 1.950

6.  Prebiotic microreactors: a synthesis of purines and dihydroxy compounds in aqueous aerosol.

Authors:  M Ruiz-Bermejo; C Menor-Salván; S Osuna-Esteban; S Veintemillas-Verdaguer
Journal:  Orig Life Evol Biosph       Date:  2006-11-29       Impact factor: 1.950

7.  Prebiotic materials from on and off the early Earth.

Authors:  Max Bernstein
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2006-10-29       Impact factor: 6.237

8.  The prebiotic synthesis of pyrimidines in frozen solution.

Authors:  H James Cleaves; Kevin E Nelson; Stanley L Miller
Journal:  Naturwissenschaften       Date:  2006-03-22

Review 9.  The role of biomacromolecular crowding, ionic strength, and physicochemical gradients in the complexities of life's emergence.

Authors:  Jan Spitzer; Bert Poolman
Journal:  Microbiol Mol Biol Rev       Date:  2009-06       Impact factor: 11.056

10.  The cold origin of life: A. Implications based on the hydrolytic stabilities of hydrogen cyanide and formamide.

Authors:  Shin Miyakawa; H James Cleaves; Stanley L Miller
Journal:  Orig Life Evol Biosph       Date:  2002-06       Impact factor: 1.950

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