Literature DB >> 11528508

A genome screen for multiple sclerosis in Sardinian multiplex families.

F Coraddu1, S Sawcer, S D'Alfonso, M Lai, A Hensiek, E Solla, S Broadley, C Mancosu, M Pugliatti, M G Marrosu, A Compston.   

Abstract

The prevalence of multiple sclerosis in Sardinia is significantly higher than in neighbouring Mediterranean countries, suggesting that the isolated growth of the population has concentrated genetic factors which increase susceptibility to the disease. The distinct HLA association of multiple sclerosis in Sardinia supports this interpretation. We have performed a whole genome screen for linkage in 49 Sardinian multiplex families using 327 markers. Non parametric linkage analysis of these data reveal suggestive linkage in the region of Chr 1q31, Chr 10q23 and Chr 11p15.

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Year:  2001        PMID： 11528508     DOI： 10.1038/sj.ejhg.5200680

Source DB:  PubMed          Journal:  Eur J Hum Genet        ISSN： 1018-4813            Impact factor:   4.246


  16 in total

Review 1.  Genetic analysis of multiple sclerosis.

Authors:  Alastair Compston; Stephen Sawcer
Journal:  Curr Neurol Neurosci Rep       Date:  2002-05       Impact factor: 5.081

Review 2.  Linkage studies of schizophrenia.

Authors:  Brien Riley
Journal:  Neurotox Res       Date:  2004       Impact factor: 3.911

Review 3.  The genetics of multiple sclerosis: an up-to-date review.

Authors:  Pierre-Antoine Gourraud; Hanne F Harbo; Stephen L Hauser; Sergio E Baranzini
Journal:  Immunol Rev       Date:  2012-07       Impact factor: 12.988

4.  A high-density screen for linkage in multiple sclerosis.

Authors:  Stephen Sawcer; Maria Ban; Mel Maranian; Tai Wai Yeo; Alastair Compston; Andrew Kirby; Mark J Daly; Philip L De Jager; Emily Walsh; Eric S Lander; John D Rioux; David A Hafler; Adrian Ivinson; Jacqueline Rimmler; Simon G Gregory; Silke Schmidt; Margaret A Pericak-Vance; Eva Akesson; Jan Hillert; Pameli Datta; Annette Oturai; Lars P Ryder; Hanne F Harbo; Anne Spurkland; Kjell-Morten Myhr; Mikko Laaksonen; David Booth; Robert Heard; Graeme Stewart; Robin Lincoln; Lisa F Barcellos; Stephen L Hauser; Jorge R Oksenberg; Shannon J Kenealy; Jonathan L Haines
Journal:  Am J Hum Genet       Date:  2005-07-29       Impact factor: 11.025

5.  Eae19, a new locus on rat chromosome 15 regulating experimental autoimmune encephalomyelitis.

Authors:  Jian Rong Sheng; Maja Jagodic; Ingrid Dahlman; Kristina Becanovic; Rita Nohra; Monica Marta; Ellen Iacobaeus; Tomas Olsson; Erik Wallström
Journal:  Genetics       Date:  2005-02-16       Impact factor: 4.562

6.  The genetic aspects of multiple sclerosis.

Authors:  Stephen Sawcer
Journal:  Ann Indian Acad Neurol       Date:  2009-10       Impact factor: 1.383

7.  Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study.

Authors:  Margaret A Pericak-Vance; Jackie B Rimmler; Jonathan L Haines; Melissa E Garcia; Jorge R Oksenberg; Lisa F Barcellos; Robin Lincoln; Stephen L Hauser; Isabelle Cournu-Rebeix; Ariele Azoulay-Cayla; Olivier Lyon-Caen; Bertrand Fontaine; Emmanuelle Duhamel; Helene Coppin; David Brassat; Marie-Paule Roth; Michel Clanet; Mehdi Alizadeh; Jacqueline Yaouanq; Erwann Quelvennec; Gilbert Semana; Gilles Edan; Marie-Claude Babron; Emmanuelle Genin; Francoise Clerget-Darpoux
Journal:  Neurogenetics       Date:  2003-11-01       Impact factor: 2.660

8.  Meta-analysis of genome-wide linkage studies across autoimmune diseases.

Authors:  Paola Forabosco; Emmanuelle Bouzigon; Mandy Y Ng; Jane Hermanowski; Sheila A Fisher; Lindsey A Criswell; Cathryn M Lewis
Journal:  Eur J Hum Genet       Date:  2008-09-10       Impact factor: 4.246

9.  A genome-wide scan in forty large pedigrees with multiple sclerosis.

Authors:  Cristen J Willer; David A Dyment; Stacey Cherny; Sreeram V Ramagopalan; Blanca M Herrera; Katie M E Morrison; A Dessa Sadovnick; Neil J Risch; George C Ebers
Journal:  J Hum Genet       Date:  2007-11-15       Impact factor: 3.172

10.  Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis.

Authors:  J L McCauley; R L Zuvich; Y Bradford; S J Kenealy; N Schnetz-Boutaud; S G Gregory; S L Hauser; J R Oksenberg; D P Mortlock; M A Pericak-Vance; J L Haines
Journal:  Genes Immun       Date:  2009-07-23       Impact factor: 2.676
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