Literature DB >> 11516963

Wnt signalling: antagonistic Dickkopfs.

A M Zorn1.   

Abstract

Dickkopf proteins are secreted antagonists of the Wnt cell signalling molecules, which have a novel mode of action. Dickkopf1 binds to the LRP5/6 Wnt co-receptor and prevents the formation of active Wnt--Frizzled--LRP5/6 receptor complexes, thus blocking the canonical Wnt--beta-catenin pathway.

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Year:  2001        PMID： 11516963     DOI： 10.1016/s0960-9822(01)00360-8

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  66 in total

1.  A genomewide survey of developmentally relevant genes in Ciona intestinalis. VI. Genes for Wnt, TGFbeta, Hedgehog and JAK/STAT signaling pathways.

Authors:  Kyosuke Hino; Yutaka Satou; Kasumi Yagi; Nori Satoh
Journal:  Dev Genes Evol       Date:  2003-05-09       Impact factor: 0.900

2.  Tfap2a and Foxd3 regulate early steps in the development of the neural crest progenitor population.

Authors:  Wen-Der Wang; David B Melville; Mercedes Montero-Balaguer; Antonis K Hatzopoulos; Ela W Knapik
Journal:  Dev Biol       Date:  2011-09-22       Impact factor: 3.582

3.  Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis.

Authors:  Fei Liu; Emily Y Chu; Brenda Watt; Yuhang Zhang; Natalie M Gallant; Thomas Andl; Steven H Yang; Min-Min Lu; Stefano Piccolo; Ruth Schmidt-Ullrich; Makoto M Taketo; Edward E Morrisey; Radhika Atit; Andrzej A Dlugosz; Sarah E Millar
Journal:  Dev Biol       Date:  2007-10-23       Impact factor: 3.582

4.  The roles of Wnt antagonists Dkk1 and sFRP4 during adipogenesis of human adipose tissue-derived mesenchymal stem cells.

Authors:  J-R Park; J-W Jung; Y-S Lee; K-S Kang
Journal:  Cell Prolif       Date:  2008-12       Impact factor: 6.831

5.  IL-1β Enhances Wnt Signal by Inhibiting DKK1.

Authors:  Yusuke Yoshida; Satoshi Yamasaki; Katsuhiro Oi; Tatsuomi Kuranobu; Takaki Nojima; Shigeru Miyaki; Hiroaki Ida; Eiji Sugiyama
Journal:  Inflammation       Date:  2018-10       Impact factor: 4.092

6.  Expression of Wnt, Frizzled, sFRP, and DKK genes in adult human pancreas.

Authors:  R Scott Heller; Tino Klein; Zhidong Ling; Harry Heimberg; Masaru Katoh; Ole D Madsen; Palle Serup
Journal:  Gene Expr       Date:  2003

7.  Wnt ligand expression in malignant melanoma: pilot study indicating correlation with histopathological features.

Authors:  K Pham; T Milovanovic; R J Barr; T Truong; R F Holcombe
Journal:  Mol Pathol       Date:  2003-10

8.  Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is required for the development of ischemic neuronal death.

Authors:  Irene Cappuccio; Agata Calderone; Carla L Busceti; Francesca Biagioni; Fabrizio Pontarelli; Valeria Bruno; Marianna Storto; Georg T Terstappen; Giovanni Gaviraghi; Francesco Fornai; Giuseppe Battaglia; Daniela Melchiorri; R Suzanne Zukin; Suzanne Zukin; Ferdinando Nicoletti; Andrea Caricasole
Journal:  J Neurosci       Date:  2005-03-09       Impact factor: 6.167

9.  The canonical Wnt/β-catenin signaling pathway stimulates herpes simplex virus 1 productive infection.

Authors:  Liqian Zhu; Clinton Jones
Journal:  Virus Res       Date:  2018-08-02       Impact factor: 3.303

Review 10.  Novel immunotherapies.

Authors:  Qing Yi
Journal:  Cancer J       Date:  2009 Nov-Dec       Impact factor: 3.360
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