Literature DB >> 1150306

Extensions to pedigree analysis I. Likehood calculations for simple and complex pedigrees.

K Lange, R C Elston.   

Abstract

A graph theoretic definition of pedigrees is given and a distinction drawn between simple and complex pedigrees. Algorithms are presented to calculate the likeihood of any kind of pedigree, assuming only segregation at a finite set of loci, nonassortative mating and no environmental correlations; multiple births and consanguineous marriages are explicity allowed for. The formulation given can lead to more powerful genetic counselling, segregation analysis and linkage analysis.

Mesh：

Year:  1975        PMID： 1150306     DOI： 10.1159/000152714

Source DB:  PubMed          Journal:  Hum Hered        ISSN： 0001-5652            Impact factor:   0.444


  40 in total

1.  Blocking Gibbs sampling for linkage analysis in large pedigrees with many loops.

Authors:  C S Jensen; A Kong
Journal:  Am J Hum Genet       Date:  1999-09       Impact factor: 11.025

2.  An optimal algorithm for automatic genotype elimination.

Authors:  J R O'Connell; D E Weeks
Journal:  Am J Hum Genet       Date:  1999-12       Impact factor: 11.025

3.  Likelihoods of multilocus DNA fingerprints in extended families.

Authors:  B Bockel; P Nürnberg; M Krawczak
Journal:  Am J Hum Genet       Date:  1992-09       Impact factor: 11.025

Review 4.  Linkage analysis in the next-generation sequencing era.

Authors:  Joan E Bailey-Wilson; Alexander F Wilson
Journal:  Hum Hered       Date:  2011-12-23       Impact factor: 0.444

5.  Genome-wide scan for self-rating of the effects of alcohol in American Indians.

Authors:  Cindy L Ehlers; Ian R Gizer; Marc A Schuckit; Kirk C Wilhelmsen
Journal:  Psychiatr Genet       Date:  2010-10       Impact factor: 2.458

6.  Online system for faster multipoint linkage analysis via parallel execution on thousands of personal computers.

Authors:  M Silberstein; A Tzemach; N Dovgolevsky; M Fishelson; A Schuster; D Geiger
Journal:  Am J Hum Genet       Date:  2006-05-01       Impact factor: 11.025

7.  An approximation to the likelihood for a pedigree with loops.

Authors:  T Wang; R L Fernando; C Stricker; R C Elston
Journal:  Theor Appl Genet       Date:  1996-12       Impact factor: 5.699

8.  An algorithm to approximate the likelihood for pedigree data with loops by cutting.

Authors:  C Stricker; R L Fernando; R C Elston
Journal:  Theor Appl Genet       Date:  1995-11       Impact factor: 5.699

Review 9.  Haplotyping methods for pedigrees.

Authors:  Guimin Gao; David B Allison; Ina Hoeschele
Journal:  Hum Hered       Date:  2009-01-27       Impact factor: 0.444

10.  Major gene analysis of quantitative variation in blood clotting factor X levels.

Authors:  R M Siervogel; R C Elston; R H Lester; J B Graham
Journal:  Am J Hum Genet       Date:  1979-03       Impact factor: 11.025
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