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Literature DB >> 11498581

The centromere paradox: stable inheritance with rapidly evolving DNA.

Abstract

Every eukaryotic chromosome has a centromere, the locus responsible for poleward movement at mitosis and meiosis. Although conventional loci are specified by their DNA sequences, current evidence favors a chromatin-based inheritance mechanism for centromeres. The chromosome segregation machinery is highly conserved across all eukaryotes, but the DNA and protein components specific to centromeric chromatin are evolving rapidly. Incompatibilities between rapidly evolving centromeric components may be responsible for both the organization of centromeric regions and the reproductive isolation of emerging species.

Entities: Disease

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Year: 2001 PMID： 11498581 DOI： 10.1126/science.1062939

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

530 in total

Review 1. Variation in satellite DNA profiles--causes and effects.

Authors: Durdica Ugarković; Miroslav Plohl
Journal: EMBO J Date: 2002-11-15 Impact factor: 11.598

2. Evidence for a fast, intrachromosomal conversion mechanism from mapping of nucleotide variants within a homogeneous alpha-satellite DNA array.

Authors: Dirk Schindelhauer; Tobias Schwarz
Journal: Genome Res Date: 2002-12 Impact factor: 9.043

3. X-autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographic patterns within species.

Authors: Joseph Lachance; John R True
Journal: Evolution Date: 2010-08-19 Impact factor: 3.694

4. CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein family, is required for efficient inner kinetochore assembly in the pathogenic yeast Candida albicans.

Authors: Babhrubahan Roy; Laura S Burrack; Museer A Lone; Judith Berman; Kaustuv Sanyal
Journal: Mol Microbiol Date: 2011-02-10 Impact factor: 3.501

The centromere paradox: stable inheritance with rapidly evolving DNA.

Review 1. Variation in satellite DNA profiles--causes and effects.

2. Evidence for a fast, intrachromosomal conversion mechanism from mapping of nucleotide variants within a homogeneous alpha-satellite DNA array.

3. X-autosome incompatibilities in Drosophila melanogaster: tests of Haldane's rule and geographic patterns within species.

4. CaMtw1, a member of the evolutionarily conserved Mis12 kinetochore protein family, is required for efficient inner kinetochore assembly in the pathogenic yeast Candida albicans.

5. Partitioning of the maize epigenome by the number of methyl groups on histone H3 lysines 9 and 27.

Review 6. RNA interference, transposons, and the centromere.

7. Marcus rhoades, preferential segregation and meiotic drive.

Review 8. Understanding eukaryotic chromosome segregation from a comparative biology perspective.

9. Satellite repeats in the functional centromere and pericentromeric heterochromatin of Medicago truncatula.

10. A single gene causes both male sterility and segregation distortion in Drosophila hybrids.