Literature DB >> 1149794

Muscarinic receptors in rat intestinal muscle: comparison with the guinea pig.

I K Taylor, A W Cuthbert, M Young.   

Abstract

The properties of muscarinic receptors in rat intestinal muscle have been investigated by examining the binding of 3H-propylbenzilylcholine mustard, 3H-PrBCM, a specific and virtually irreversible muscarinic antagonist. It is shown that the properties of these muscarinic receptore correspond in general closely to those observed in the guinea pig, in particular the binding curve inferred for carbachol shows the same apparent negative cooperativity, but there is a notable difference in the rate of binding 3H-PrBCM.

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Year:  1975        PMID: 1149794     DOI: 10.1016/0014-2999(75)90055-2

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  7 in total

1.  Ligand binding to muscarinic receptors in intact longitudinal muscle strips from guinea-pig intestine.

Authors:  D Ward; J M Young
Journal:  Br J Pharmacol       Date:  1977-10       Impact factor: 8.739

2.  Muscarinic receptors in rat sympathetic ganglia.

Authors:  D A Brown; S Fatherazi; J Garthwaite; R D White
Journal:  Br J Pharmacol       Date:  1980-12       Impact factor: 8.739

3.  Histamine H1-receptors in the brain of the guinea-pig and the rat: differences in ligand binding properties and regional distribution.

Authors:  S J Hill; J M Young
Journal:  Br J Pharmacol       Date:  1980-04       Impact factor: 8.739

4.  Evidence that histamine and carbachol may open the same ion channels in longitudinal smooth muscle of guinea-pig ileum.

Authors:  T B Bolton; J P Clark; K Kitamura; R J Lang
Journal:  J Physiol       Date:  1981-11       Impact factor: 5.182

5.  Actions of various muscarinic agonists on membrane potential, potassium efflux, and contraction of longitudinal muscle of guinea-pig intestine.

Authors:  T B Bolton; J P Clark
Journal:  Br J Pharmacol       Date:  1981-02       Impact factor: 8.739

6.  Comparative studies of the postjunctional activities of some very potent muscarinic agonists.

Authors:  E Grana; A Lucchelli; F Zonta; M G Santagostino-Barbone; G D'Agostino
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-03       Impact factor: 3.000

7.  Ligand-binding propeties of the muscarinic acetylcholine receptor in mouse neuroblastoma cells.

Authors:  P G Strange; N J Birdsall; A S Burgen
Journal:  Biochem J       Date:  1978-06-15       Impact factor: 3.857

  7 in total

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