Literature DB >> 114952

Fibroblast implantation enhances wound healing as indicated by breaking strength determinations.

W W Krueger, H Goepfert, M Romsdahl, J Herson, R H Withers, R H Jesse.   

Abstract

Irradiation of normal tissues at the dose/time factor employed in the treatment of solid tumors impairs the subsequent healing of surgical wounds made in those tissues. Irreversible radiation damage to regional fibroblasts is one cause of impaired healing. This study was conducted to determine whether syngeneic guinea pig fibroblasts, harvested from tissue culture when injected into irradiated guinea pig skin at the time of wound closure, could improve wound healing. Breaking strength determinations indicate that irradiated wounds demonstrate enhanced wound healing if implanted with fibroblasts.

Entities:  

Mesh：

Year:  1978        PMID： 114952     DOI： 10.1177/019459987808600527

Source DB:  PubMed          Journal:  Otolaryngology        ISSN： 0161-6439


  6 in total

1.  Reconstruction of the perineum following anorectal cancer excision.

Authors:  Nicola Petrie; Graham Branagan; Caroline McGuiness; Shaun McGee; Clare Fuller; Helen Chave
Journal:  Int J Colorectal Dis       Date:  2008-08-08       Impact factor: 2.571

2.  Free latissimus dorsi myocutaneous flap for pelvic floor reconstruction following pelvic exenteration.

Authors:  Ahmed Hossamedine Abdou; Lei Li; Karl Khatib-Chahidi; Achim Troja; Phillip Looft; Eva Monika Gudewer; Hans-Rudolf Raab; Dalibor Antolovic
Journal:  Int J Colorectal Dis       Date:  2015-09-26       Impact factor: 2.571

3.  Mitigation of Lethal Radiation Syndrome in Mice by Intramuscular Injection of 3D Cultured Adherent Human Placental Stromal Cells.

Authors:  Elena Gaberman; Lena Pinzur; Lilia Levdansky; Maria Tsirlin; Nir Netzer; Zami Aberman; Raphael Gorodetsky
Journal:  PLoS One       Date:  2013-06-18       Impact factor: 3.240

4.  Pelvi-perineal flap reconstruction: normal imaging appearances and post-operative complications on cross-sectional imaging.

Authors:  Nyree Griffin; Jeremy Rabouhans; Lee A Grant; Roy L H Ng; David Ross; Paul Roblin; Mark L George
Journal:  Insights Imaging       Date:  2011-02-02

Review 5.  Allogenic Use of Human Placenta-Derived Stromal Cells as a Highly Active Subtype of Mesenchymal Stromal Cells for Cell-Based Therapies.

Authors:  Raphael Gorodetsky; Wilhelm K Aicher
Journal:  Int J Mol Sci       Date:  2021-05-18       Impact factor: 5.923

6.  Marrow-derived stromal cell delivery on fibrin microbeads can correct radiation-induced wound-healing deficits.

Authors:  Michael W Xie; Raphael Gorodetsky; Ewa D Micewicz; Ewa D Micevicz; Natalia C Mackenzie; Elena Gaberman; Lilia Levdansky; William H McBride
Journal:  J Invest Dermatol       Date:  2012-09-06       Impact factor: 8.551
  6 in total

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