Literature DB >> 1149051

Photochemotherapy of glioma cells by visible light and hematoporphyrin.

S G Granelli, I Diamond, A F McDonagh, C B Wilson, S L Nielsen.   

Abstract

Malignant tumors take up and retain hematoporphyrin to a much greater extent than do normal tissues. Porphyrins are photodynamic agents that sensitize cells so that they are damaged by exposure to light. Treatment with hematoporphyrin followed by irradiation with light can destroy glioma cells in culture in less than 8 min and gliomas growing s.c. in rats in about 40 min. Photochemotherapy may become useful in the management of malignant tumors that are resistant to current methods of treatment.

Entities:  

Mesh：

Substances：

Year:  1975        PMID： 1149051

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  7 in total

1.  Photosensitization and the nervous system in the planarian Dugesia gonocephala. A histochemical, ultrastructural and behavioral investigation.

Authors:  G Palladini; V Margotta; L Medolago-Albani; M C Hernandez; A Carolei; T de Michele
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

2.  Observations in studies of quantitative kinetics of tritium labelled hematoporphyrin derivatives (HpDI and HpDII) in the normal and neoplastic rat brain model.

Authors:  F M Little; C J Gomer; S Hyman; M L Apuzzo
Journal:  J Neurooncol       Date:  1984       Impact factor: 4.130

3.  Preferential delivery of liposome-incorporated porphyrins to neoplastic cells in tumour-bearing rats.

Authors:  G Jori; L Tomio; E Reddi; E Rossi; L Corti; P L Zorat; F Calzavara
Journal:  Br J Cancer       Date:  1983-08       Impact factor: 7.640

4.  The mechanism of photodynamic inactivation of human cells in vitro in the presence of haematoporphyrin.

Authors:  J Moan; E O Pettersen; T Christensen
Journal:  Br J Cancer       Date:  1979-04       Impact factor: 7.640

Review 5.  Chemophototherapy: An Emerging Treatment Option for Solid Tumors.

Authors:  Dandan Luo; Kevin A Carter; Dyego Miranda; Jonathan F Lovell
Journal:  Adv Sci (Weinh)       Date:  2016-05-24       Impact factor: 16.806

6.  In vivo biological activity of the components of haematoporphyrin derivative.

Authors:  M C Berenbaum; R Bonnett; P A Scourides
Journal:  Br J Cancer       Date:  1982-04       Impact factor: 7.640

Review 7.  Role of Photoactive Phytocompounds in Photodynamic Therapy of Cancer.

Authors:  Kasipandi Muniyandi; Blassan George; Thangaraj Parimelazhagan; Heidi Abrahamse
Journal:  Molecules       Date:  2020-09-08       Impact factor: 4.411
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.