Literature DB >> 11490250

Radical cystectomy is safe in elderly patients at high risk.

S S Chang1, G Alberts, M S Cookson, J A Smith.   

Abstract

PURPOSE: Radical cystectomy is standard treatment for bladder cancer in healthy individuals. We determined the safety of radical cystectomy in elderly patients at high risk.
MATERIALS AND METHODS: We reviewed the records of all patients who underwent radical cystectomy at our institution between January 1994 and June 2000. Of these 382 patients we identified 44 who were elderly and at high risk, as defined by age 75 years or greater and American Society of Anesthesiologists classification 3 or greater. We examined postoperative care, perioperative minor/major complications, the mortality rate and the need for rehospitalization.
RESULTS: Median age of the 44 patients was 77.5 years (range 75 to 87). American Society of Anesthesiologists class was 3 in 40 patients and 4 in 4. Median hospitalization was 7 days (range 4 to 20). Postoperatively 31 of the 44 patients (70%) were transferred directly to the general urology floor, while cardiac monitoring was required postoperatively in 30%. Nine of these patients were transferred to a step-down unit and the remaining 4 required surgical intensive care unit admission. Minor and major complications developed in 10 (22.7%) and 2 (4.5%) cases, respectively. No patients died in the perioperative period and 4 patients were hospitalized within 6 months of discharge home.
CONCLUSIONS: Our results support the safety of radical cystectomy in elderly patients at high risk. Acceptable perioperative morbidity and mortality may be achieved without routine intensive monitoring postoperatively.

Entities:  

Mesh:

Year:  2001        PMID: 11490250

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  19 in total

1.  Radical cystectomy in patients over 70 years of age: impact of comorbidity on perioperative morbidity and mortality.

Authors:  Vladimir Novotny; Stefan Zastrow; Rainer Koch; Manfred P Wirth
Journal:  World J Urol       Date:  2011-11-02       Impact factor: 4.226

2.  Radical cystectomy in septuagenarian patients with bladder cancer.

Authors:  Narmada P Gupta; Rajiv Goel; Ashok K Hemal; P N Dogra; Amlesh Seth; Monish Aron; Rajeev Kumar; M S Ansari
Journal:  Int Urol Nephrol       Date:  2004       Impact factor: 2.370

3.  Prognostic impact of comorbidity in patients with bladder cancer.

Authors:  Ifeanyichukwu I Megwalu; Anna Vlahiotis; Mohamed Radwan; Jay F Piccirillo; Adam S Kibel
Journal:  Eur Urol       Date:  2007-11-05       Impact factor: 20.096

Review 4.  Bladder cancer.

Authors:  David J Gallagher; Matthew I Milowsky
Journal:  Curr Treat Options Oncol       Date:  2009-08

Review 5.  [Long-term follow-up of the defunctionalized bladder after urinary diversion].

Authors:  F-C von Rundstedt; D Lazica; A S Brandt; M J Mathers; S Roth
Journal:  Urologe A       Date:  2010-01       Impact factor: 0.639

6.  [Geriatric assessment. Is it significantly helpful in selection of elderly tumour patients for a difficult therapy?].

Authors:  S Krege; C Friedrich; G Lümmen; L Pientka; H Rübben
Journal:  Urologe A       Date:  2004-08       Impact factor: 0.639

7.  Ileal conduit urinary diversion in patients with previous history of abdominal/pelvic irradiation.

Authors:  Sam S Chang; Gregory L Alberts; Joseph A Smith; Michael S Cookson
Journal:  World J Urol       Date:  2004-09-21       Impact factor: 4.226

Review 8.  [Cystectomy in the elderly patient].

Authors:  G Bartsch; K Gust; S Vallo; C Bartsch; I Tsaur; J Mani; A Haferkamp
Journal:  Urologe A       Date:  2013-06       Impact factor: 0.639

9.  Radical cystectomy for invasive bladder cancer: long-term results of a standard procedure.

Authors:  John P Stein; Donald G Skinner
Journal:  World J Urol       Date:  2006-03-04       Impact factor: 4.226

10.  Comparative survival following different treatment modalities for stage T2 bladder cancer in octogenarians.

Authors:  Jerry J Trulson; Pranav Sharma; Tyler Haden; Emil Kheterpal; Naveen Pokala
Journal:  World J Urol       Date:  2013-07-02       Impact factor: 4.226

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