Literature DB >> 11479363

The intrarenal endothelin system and hypertension.

Z A Abassi1, S Ellahham, J Winaver, A Hoffman.   

Abstract

The kidney is both a source of endothelin (ET) generation and an important target organ of this peptide. The highest concentrations of ET-1 in the body exist in the renal medulla, where it mediates natriuretic and diuretic effects through the ET(B) receptor subtype. It is proposed that aberrations in the renal ET system may lead to sodium and water retention and subsequently to the development of hypertension.

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Year:  2001        PMID： 11479363     DOI： 10.1152/physiologyonline.2001.16.4.152

Source DB:  PubMed          Journal:  News Physiol Sci        ISSN： 0886-1714


  10 in total

1.  Cooperative role of ETA and ETB receptors in mediating the diuretic response to intramedullary hyperosmotic NaCl infusion.

Authors:  Erika I Boesen; David M Pollock
Journal:  Am J Physiol Renal Physiol       Date:  2010-09-15

Review 2.  Physiology of endothelin and the kidney.

Authors:  Donald E Kohan; Edward W Inscho; Donald Wesson; David M Pollock
Journal:  Compr Physiol       Date:  2011-04       Impact factor: 9.090

Review 3.  Regulation of blood pressure and salt homeostasis by endothelin.

Authors:  Donald E Kohan; Noreen F Rossi; Edward W Inscho; David M Pollock
Journal:  Physiol Rev       Date:  2011-01       Impact factor: 37.312

4.  Cardiac-specific knockout of ET(A) receptor mitigates low ambient temperature-induced cardiac hypertrophy and contractile dysfunction.

Authors:  Yingmei Zhang; Linlin Li; Yinan Hua; Jennifer M Nunn; Feng Dong; Masashi Yanagisawa; Jun Ren
Journal:  J Mol Cell Biol       Date:  2012-03-22       Impact factor: 6.216

5.  Aging-related kidney damage is associated with a decrease in klotho expression and an increase in superoxide production.

Authors:  Zhong Zuo; Han Lei; Xiuqing Wang; Yuhong Wang; William Sonntag; Zhongjie Sun
Journal:  Age (Dordr)       Date:  2010-09-10

Review 6.  Thick Ascending Limb Sodium Transport in the Pathogenesis of Hypertension.

Authors:  Agustin Gonzalez-Vicente; Fara Saez; Casandra M Monzon; Jessica Asirwatham; Jeffrey L Garvin
Journal:  Physiol Rev       Date:  2019-01-01       Impact factor: 37.312

Review 7.  Endothelin-1 and hypertension: from bench to bedside.

Authors:  Donald E Kohan
Journal:  Curr Hypertens Rep       Date:  2008-02       Impact factor: 5.369

8.  Endothelin-1 inhibits thick ascending limb transport via Akt-stimulated nitric oxide production.

Authors:  Marcela Herrera; Nancy J Hong; Pablo A Ortiz; Jeffrey L Garvin
Journal:  J Biol Chem       Date:  2008-11-25       Impact factor: 5.157

9.  The association of an adenine insertion variant in the 5'UTR of the endothelin-1 gene with hypertension and orthostatic hypotension.

Authors:  Xiao-Han Fan; Hu Wang; Ling-Gen Gao; Kai Sun; Xiang-Liang Zhou; Ru-Tai Hui
Journal:  Arch Med Sci       Date:  2012-05-09       Impact factor: 3.318

Review 10.  Cardiovascular responses to cold exposure.

Authors:  Zhongjie Sun
Journal:  Front Biosci (Elite Ed)       Date:  2010-01-01
  10 in total

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