Literature DB >> 1147616

Emodin, a toxic metabolite of Aspergillus wentii isolated from weevil-damaged chestnuts.

J M Wells, R J Cole, J W Kirksey.   

Abstract

A diarrheagenic toxin from culture extracts of Aspergillus wentii Wehmer isolated from weevil-damaged Chinese chestnuts was identified as emodin (2-methyl-4,5,7-trihydroxyanthraquinone). The orange-red, crystalline toxin (mp 255 to 257 C) showed ultraviolet absorption maxima in ethyl alcohol at 223, 250, 267, 290, and 442 nm, and infrared absorption maxima at 3,400 cm-1 (OH), 1,635, and 1,625 CM-1. Chemical shifts and coupling constants of the proton magnetic resonance spectra of the A. wentii toxin and of authentic emodin agreed. Mean lethal dose of emodin orally administered to 1-day-old DeKalb cockerels was 3.7 mg/kg.

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Year:  1975        PMID： 1147616      PMCID： PMC187107          DOI： 10.1128/am.30.1.26-28.1975

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  10 in total

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Authors:  G AGOSTI; J H BIRKINSHAW; P CHAPLEN
Journal:  Biochem J       Date:  1962-12       Impact factor: 3.857

2.  ANTHRAQUINONE METABOLITES OF TALAROMYCES AVELLANEUS (THOM ET TURRESON) C. R. BENJAMIN AND PREUSSIA MULTISPORA (SAITO ET MINOURA) CAIN.

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Journal:  Chem Pharm Bull (Tokyo)       Date:  1965-03       Impact factor: 1.645

3.  Ultraviolet absorption spectra of some polyhydroxyanthraquinones.

Authors:  J H BIRKINSHAW
Journal:  Biochem J       Date:  1955-03       Impact factor: 3.857

4.  Metabolic products of fungi. XI. Some observation on the occurrence of skyrin and rugulosin in mold metabolites, with a reference to structural relationship between penicilliopsin and skyrin.

Authors:  S SHIBATA; J SHOJI; A OHTA; M WATANABE
Journal:  Pharm Bull       Date:  1957-08

5.  The structure of dermocybin.

Authors:  J H Birkinshaw; R Gourlay
Journal:  Biochem J       Date:  1961-08       Impact factor: 3.857

6.  Toxic metabolite produced by Aspergillus wentii.

Authors:  M T Wu; J C Ayres; P E Koehler; G Chassis
Journal:  Appl Microbiol       Date:  1974-02

7.  Toxic effects of oosporein from Chaetomium trilaterale.

Authors:  R J Cole; J W Kirksey; H G Cutler; E E Davis
Journal:  J Agric Food Chem       Date:  1974 May-Jun       Impact factor: 5.279

8.  Mycotoxins in Aspergillus.

Authors:  G Semeniuk; G S Harshfield; C W Carlson; C W Hesseltine; W F Kwolek
Journal:  Mycopathol Mycol Appl       Date:  1971-02-19

9.  Production of aflatoxin by Aspergillus wentii Wehmer.

Authors:  H W Schroeder; M J Verrett
Journal:  Can J Microbiol       Date:  1969-08       Impact factor: 2.419

10.  Aflatoxin: a metabolic product of several fungi.

Authors:  M M Kulik; C E Holaday
Journal:  Mycopathol Mycol Appl       Date:  1966-11-10
  10 in total
  19 in total

1.  Curvularia lunata, a New Source of Cytochalasin B.

Authors:  J M Wells; R J Cole; H C Cutler; D H Spalding
Journal:  Appl Environ Microbiol       Date:  1981-04       Impact factor: 4.792

2.  Isolation and Characterization of Sexual Spore Pigments from Aspergillus nidulans.

Authors:  D W Brown; J J Salvo
Journal:  Appl Environ Microbiol       Date:  1994-03       Impact factor: 4.792

3.  Metabolic products of microorganisms. 192. The anthraquinones of the Aspergillus glaucus group. II. Biological activity.

Authors:  H Anke; I Kolthoum; H Laatsch
Journal:  Arch Microbiol       Date:  1980-07       Impact factor: 2.552

4.  Phytotoxic, Antifungal and Immunosuppressive Metabolites from Aspergillus terreus QT122 Isolated from the Gut of Dragonfly.

Authors:  Yi-Hui Lu; Li-Ping Jin; Li-Chun Kong; Ying-Lao Zhang
Journal:  Curr Microbiol       Date:  2016-11-14       Impact factor: 2.188

5.  Toxigenic Aspergillus and Penicillium isolates from weevil-damaged chestnuts.

Authors:  J M Wells; J A Payne
Journal:  Appl Microbiol       Date:  1975-10

6.  Chemotaxonomy of the genus Talaromyces.

Authors:  J C Frisvad; O Filtenborg; R A Samson; A C Stolk
Journal:  Antonie Van Leeuwenhoek       Date:  1990-04       Impact factor: 2.271

7.  Polyphasic taxonomy of Aspergillus section Aspergillus (formerly Eurotium), and its occurrence in indoor environments and food.

Authors:  A J Chen; V Hubka; J C Frisvad; C M Visagie; J Houbraken; M Meijer; J Varga; R Demirel; Ž Jurjević; A Kubátová; F Sklenář; Y G Zhou; R A Samson
Journal:  Stud Mycol       Date:  2017-07-12       Impact factor: 16.097

8.  Studies on toxigenic fungi in roasted foodstuff (salted seed) and halotolerant activity of emodin-producing Aspergillus wentii.

Authors:  H A Hasan
Journal:  Folia Microbiol (Praha)       Date:  1998       Impact factor: 2.099

9.  Mutagenicity of the mycotoxin emodin in the salmonella/microsome system.

Authors:  F C Wehner; P G Thiel; M du Rand
Journal:  Appl Environ Microbiol       Date:  1979-03       Impact factor: 4.792

10.  The isolation and identification of some toxic constituents ofAspergillus wentii wehmer.

Authors:  C J Rabie; P S Steyn; F R van Heerden
Journal:  Mycotoxin Res       Date:  1986-03       Impact factor: 3.833
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