PURPOSE: The purpose of this study was to evaluate the MR findings of ganglioneuroma and to correlate imaging and histologic features. METHOD: Conventional SE and contrast-enhanced dynamic MRI was used to examine 10 patients with pathologically confirmed ganglioneuroma. The morphologic features, signal intensity, and dynamic enhancement pattern of the tumors were retrospectively analyzed and correlated with histologic features. RESULTS: Capsules were present in all tumors histologically and were also detected in five tumors on postcontrast T1-weighted images. A whorled appearance corresponding to interlacing bundles of Schwann cells and collagen fibers on histologic specimens was visualized in five tumors on T1-and/or T2-weighted images. Tumors with markedly high signal intensity on T2-weighted images consisted histologically of a large amount of myxoid stroma and relatively few cellular and fibrous components. Tumors with intermediate to high signal intensity consisted of numerous cellular and fibrous components and little myxoid stroma. Early enhancement of tumors was usually lacking in dynamic MR studies; however enhancement gradually increased. CONCLUSION: The results suggest that the MR features of ganglioneuroma are well correlated with histologic findings.
PURPOSE: The purpose of this study was to evaluate the MR findings of ganglioneuroma and to correlate imaging and histologic features. METHOD: Conventional SE and contrast-enhanced dynamic MRI was used to examine 10 patients with pathologically confirmed ganglioneuroma. The morphologic features, signal intensity, and dynamic enhancement pattern of the tumors were retrospectively analyzed and correlated with histologic features. RESULTS: Capsules were present in all tumors histologically and were also detected in five tumors on postcontrast T1-weighted images. A whorled appearance corresponding to interlacing bundles of Schwann cells and collagen fibers on histologic specimens was visualized in five tumors on T1-and/or T2-weighted images. Tumors with markedly high signal intensity on T2-weighted images consisted histologically of a large amount of myxoid stroma and relatively few cellular and fibrous components. Tumors with intermediate to high signal intensity consisted of numerous cellular and fibrous components and little myxoid stroma. Early enhancement of tumors was usually lacking in dynamic MR studies; however enhancement gradually increased. CONCLUSION: The results suggest that the MR features of ganglioneuroma are well correlated with histologic findings.
Authors: Joon-Hyop Lee; Young Jun Chai; Tae-Hyung Kim; June Young Choi; Kyu Eun Lee; Hyun-Young Kim; Yoo-Seok Yoon; Hyeon Hoe Kim Journal: World J Surg Date: 2016-12 Impact factor: 3.352
Authors: Mariaelena Occhipinti; Benedikt H Heidinger; Elisa Franquet; Ronald L Eisenberg; Alexander A Bankier Journal: Diagn Interv Radiol Date: 2015 Jul-Aug Impact factor: 2.630
Authors: G N Zografos; K Kothonidis; C Ageli; N Kopanakis; K Dimitriou; E Papaliodi; G Kaltsas; M Pagoni; G Papastratis Journal: JSLS Date: 2007 Oct-Dec Impact factor: 2.172