Diffusion property in a hamartomatous lesion of neurofibromatosis type 1.

Though diffusion-weighted MRI has been applied to various intracranial lesions, few reports had been presented about cerebral hamartomatous lesions in patients with neurofibromatosis type 1 (NF1). In this study, we report the interval changes of apparent diffusion coefficient (ADC) in a presumed hamartomatous lesion. In our case, the ADC increased slightly over a 3 year period. This diffusion property may provide specific insight into the etiology of cerebral hamartomatous lesions observed in NF1.