Literature DB >> 11461045

Configuration and racemization determination of cysteine residues in peptides by chiral derivatization and HPLC: application to oxytocin peptides.

S Szabó1, G Szókán, A M Khlafulla, M Almás, C Kiss, A Rill, I Schön.   

Abstract

An improved RP-HPLC method was developed for the determination of the configuration and stereochemical purity of cysteine residues in peptides. The method consists of oxidation of cysteine and cystine residues to cysteic acid, followed by hydrolysis and pre-column chiral derivatization with Val-Marfey's reagent.

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Year:  2001        PMID： 11461045     DOI： 10.1002/psc.325

Source DB:  PubMed          Journal:  J Pept Sci        ISSN： 1075-2617            Impact factor:   1.905


  3 in total

1.  Histone deacetylase inhibitors from Burkholderia thailandensis.

Authors:  Paul Klausmeyer; Suzanne M Shipley; Karina M Zuck; Thomas G McCloud
Journal:  J Nat Prod       Date:  2011-10-03       Impact factor: 4.050

2.  Thiazoline peptides and a tris-phenethyl urea from Didemnum molle with anti-HIV activity.

Authors:  Zhenyu Lu; Mary Kay Harper; Christopher D Pond; Louis R Barrows; Chris M Ireland; Ryan M Van Wagoner
Journal:  J Nat Prod       Date:  2012-07-30       Impact factor: 4.050

3.  Mollamides B and C, Cyclic hexapeptides from the indonesian tunicate Didemnum molle.

Authors:  Marwa S Donia; Bin Wang; Daniel C Dunbar; Prashant V Desai; Akshay Patny; Mitchell Avery; Mark T Hamann
Journal:  J Nat Prod       Date:  2008-06-11       Impact factor: 4.050
  3 in total

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