BACKGROUND AND OBJECTIVES: The purpose of this study was to evaluate the feasibility of sentinel lymph node biopsy in breast cancer patients at our institution and to report the follow-up status of node-negative patients with removal of only the sentinel node. METHODS: A total of 247 breast cancer patients underwent sentinel node (SN) mapping between June of 1996 and September of 2000. The SN was identified by using a combination of vital blue dye and a radiolabeled colloid. RESULTS: A SN was identified in 227 of 247 patients (91.9%). One hundred forty-five were SN negative, 82 were SN positive. All SN-positive patients underwent axillary dissection of level I and II, whereas 83 patients with a negative SN had SN biopsy only. Median follow-up of these patients at 22 months revealed no axillary recurrence; the morbidity resulting from SN biopsy was negligible. CONCLUSIONS: Although the follow-up is very short, SN biopsy only in node-negative breast cancer patients had no negative impact on the axillary failure rate and resulted in negligible morbidity. Copyright 2001 Wiley-Liss, Inc.
BACKGROUND AND OBJECTIVES: The purpose of this study was to evaluate the feasibility of sentinel lymph node biopsy in breast cancerpatients at our institution and to report the follow-up status of node-negative patients with removal of only the sentinel node. METHODS: A total of 247 breast cancerpatients underwent sentinel node (SN) mapping between June of 1996 and September of 2000. The SN was identified by using a combination of vital blue dye and a radiolabeled colloid. RESULTS: A SN was identified in 227 of 247 patients (91.9%). One hundred forty-five were SN negative, 82 were SN positive. All SN-positive patients underwent axillary dissection of level I and II, whereas 83 patients with a negative SN had SN biopsy only. Median follow-up of these patients at 22 months revealed no axillary recurrence; the morbidity resulting from SN biopsy was negligible. CONCLUSIONS: Although the follow-up is very short, SN biopsy only in node-negative breast cancerpatients had no negative impact on the axillary failure rate and resulted in negligible morbidity. Copyright 2001 Wiley-Liss, Inc.
Authors: Igor Langer; Walter Richard Marti; Ulrich Guller; Holger Moch; Felix Harder; Daniel Oertli; Markus Zuber Journal: Ann Surg Date: 2005-01 Impact factor: 12.969
Authors: Jacqueline S Jeruss; Lisa A Newman; Gregory D Ayers; Massimo Cristofanilli; Kristine R Broglio; Funda Meric-Bernstam; Min Yi; Jennifer F Waljee; Merrick I Ross; Kelly K Hunt Journal: Cancer Date: 2008-06-15 Impact factor: 6.860