Literature DB >> 11451702

Mutation in the DNA gyrase A Gene of Escherichia coli that expands the quinolone resistance-determining region.

S M Friedman1, T Lu, K Drlica.   

Abstract

In three Escherichia coli mutants, a change (Ala-51 to Val) in the gyrase A protein outside the standard quinolone resistance-determining region (QRDR) lowered the level of quinolone susceptibility more than changes at amino acids 67, 82, 84, and 106 did. Revision of the QRDR to include amino acid 51 is indicated.

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Year:  2001        PMID： 11451702      PMCID： PMC90659          DOI： 10.1128/AAC.45.8.2378-2380.2001

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  18 in total

1.  Prevalence of gyrA, gyrB, parC, and parE mutations in clinical isolates of Streptococcus pneumoniae with decreased susceptibilities to different fluoroquinolones and originating from Worldwide Surveillance Studies during the 1997-1998 respiratory season.

Authors:  M E Jones; D F Sahm; N Martin; S Scheuring; P Heisig; C Thornsberry; K Köhrer; F J Schmitz
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

2.  Selection of antibiotic-resistant bacterial mutants: allelic diversity among fluoroquinolone-resistant mutations.

Authors:  J Zhou; Y Dong; X Zhao; S Lee; A Amin; S Ramaswamy; J Domagala; J M Musser; K Drlica
Journal:  J Infect Dis       Date:  2000-07-24       Impact factor: 5.226

3.  Roles of gyrA mutations in resistance of clinical isolates and in vitro mutants of Bacteroides fragilis to the new fluoroquinolone trovafloxacin.

Authors:  R Bachoual; L Dubreuil; C J Soussy; J Tankovic
Journal:  Antimicrob Agents Chemother       Date:  2000-07       Impact factor: 5.191

4.  Phage P1 mutants with altered transducing abilities for Escherichia coli.

Authors:  J D Wall; P D Harriman
Journal:  Virology       Date:  1974-06       Impact factor: 3.616

5.  Molecular epidemiology of quinolone resistance and comparative in vitro activities of new quinolones against European Staphylococcus aureus isolates.

Authors:  F J Schmitz; A C Fluit; S Brisse; J Verhoef; K Köhrer; D Milatovic
Journal:  FEMS Immunol Med Microbiol       Date:  1999-12

6.  Mechanisms and frequency of resistance to premafloxacin in Staphylococcus aureus: novel mutations suggest novel drug-target interactions.

Authors:  D Ince; D C Hooper
Journal:  Antimicrob Agents Chemother       Date:  2000-12       Impact factor: 5.191

7.  Mutant prevention concentration as a measure of fluoroquinolone potency against mycobacteria.

Authors:  G Sindelar; X Zhao; A Liew; Y Dong; T Lu; J Zhou; J Domagala; K Drlica
Journal:  Antimicrob Agents Chemother       Date:  2000-12       Impact factor: 5.191

8.  Susceptibilities of Neisseria gonorrhoeae isolates containing amino acid substitutions in GyrA, with or without substitutions in ParC, to newer fluoroquinolones and other antibiotics.

Authors:  M Tanaka; H Nakayama; M Haraoka; T Saika; I Kobayashi; S Naito
Journal:  Antimicrob Agents Chemother       Date:  2000-01       Impact factor: 5.191

9.  A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.

Authors:  M Singer; T A Baker; G Schnitzler; S M Deischel; M Goel; W Dove; K J Jaacks; A D Grossman; J W Erickson; C A Gross
Journal:  Microbiol Rev       Date:  1989-03

10.  Mutations in the gene coding for Escherichia coli DNA topoisomerase I affect transcription and transposition.

Authors:  R Sternglanz; S DiNardo; K A Voelkel; Y Nishimura; Y Hirota; K Becherer; L Zumstein; J C Wang
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205
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  38 in total

1.  The alpha4 residues of human DNA topoisomerase IIalpha function in enzymatic activity and anticancer drug sensitivity.

Authors:  Namiko Suda; Yasutomo Ito; Tsuneo Imai; Toyone Kikumori; Akihiko Kikuchi; Yukihiro Nishiyama; Shonen Yoshida; Motoshi Suzuki
Journal:  Nucleic Acids Res       Date:  2004-03-16       Impact factor: 16.971

2.  Gene expression profiling of intrinsic thermotolerance in Escherichia coli.

Authors:  S Marvin Friedman; Mohammed Hossain; Tal H Hasson; Akira Kawamura
Journal:  Curr Microbiol       Date:  2006-01-02       Impact factor: 2.188

3.  Multiple resistance mechanisms acting in unison in an Escherichia coli clinical isolate.

Authors:  Dhriti Mallik; Akash Kumar; Sujoy Kumar Sarkar; Anindya S Ghosh
Journal:  Curr Microbiol       Date:  2013-08-02       Impact factor: 2.188

Review 4.  Clinical importance and epidemiology of quinolone resistance.

Authors:  Eu Suk Kim; David C Hooper
Journal:  Infect Chemother       Date:  2014-12-29

5.  Effect of anaerobic growth on quinolone lethality with Escherichia coli.

Authors:  Muhammad Malik; Syed Hussain; Karl Drlica
Journal:  Antimicrob Agents Chemother       Date:  2006-10-16       Impact factor: 5.191

6.  An allele of gyrA prevents Salmonella enterica serovar Typhimurium from using succinate as a carbon source.

Authors:  George E Schmitz; Diana M Downs
Journal:  J Bacteriol       Date:  2006-04       Impact factor: 3.490

7.  Small-colony mutants of Staphylococcus aureus allow selection of gyrase-mediated resistance to dual-target fluoroquinolones.

Authors:  Xiao-Su Pan; Penelope J Hamlyn; Raquel Talens-Visconti; Fabiana L Alovero; Ruben H Manzo; L Mark Fisher
Journal:  Antimicrob Agents Chemother       Date:  2002-08       Impact factor: 5.191

8.  Detection and identification of ciprofloxacin-resistant Yersinia pestis by denaturing high-performance liquid chromatography.

Authors:  William Hurtle; Luther Lindler; Wei Fan; David Shoemaker; Erik Henchal; David Norwood
Journal:  J Clin Microbiol       Date:  2003-07       Impact factor: 5.948

9.  Quinolone and cephalosporin resistance in enteric Fever.

Authors:  Malini Rajinder Capoor; Deepthi Nair
Journal:  J Glob Infect Dis       Date:  2010-09

10.  Mutation rate and evolution of fluoroquinolone resistance in Escherichia coli isolates from patients with urinary tract infections.

Authors:  Patricia Komp Lindgren; Asa Karlsson; Diarmaid Hughes
Journal:  Antimicrob Agents Chemother       Date:  2003-10       Impact factor: 5.191
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