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Literature DB >> 11447689

Interactions and conversions of prion protein isoforms.

B Caughey¹, G J Raymond, M A Callahan, C Wong, G S Baron, L W Xiong.

Abstract

Entities: Species

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Year: 2001 PMID： 11447689 DOI： 10.1016/s0065-3233(01)57021-7

Source DB: PubMed Journal: Adv Protein Chem ISSN： 0065-3233

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16 in total

1. Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion.

Authors: S M Uptain; G J Sawicki; B Caughey; S Lindquist
Journal: EMBO J Date: 2001-11-15 Impact factor: 11.598

2. Antibody to DNA detects scrapie but not normal prion protein.

Authors: Wen-Quan Zou; Jian Zheng; Donald M Gray; Pierluigi Gambetti; Shu G Chen
Journal: Proc Natl Acad Sci U S A Date: 2004-01-20 Impact factor: 11.205

3. The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein.

Authors: Claire Sunyach; Angela Jen; Juelin Deng; Kathleen T Fitzgerald; Yveline Frobert; Jacques Grassi; Mary W McCaffrey; Roger Morris
Journal: EMBO J Date: 2003-07-15 Impact factor: 11.598

4. Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes.

Authors: Gerald S Baron; Kathy Wehrly; David W Dorward; Bruce Chesebro; Byron Caughey
Journal: EMBO J Date: 2002-03-01 Impact factor: 11.598

Interactions and conversions of prion protein isoforms.

1. Strains of [PSI(+)] are distinguished by their efficiencies of prion-mediated conformational conversion.

2. Antibody to DNA detects scrapie but not normal prion protein.

3. The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein.

4. Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes.

5. Structural changes of membrane-anchored native PrP(C).

6. Prion infection of epithelial Rov cells is a polarized event.

7. Probing structural differences in prion protein isoforms by tyrosine nitration.

8. Sodium valproate does not augment Prpsc in murine neuroblastoma cells.

9. PrP antibody binding-induced epitope modulation evokes immunocooperativity.

10. Mouse-adapted scrapie infection of SN56 cells: greater efficiency with microsome-associated versus purified PrP-res.