| Literature DB >> 11444943 |
C S Zuo1, A Mahmood, A D Sherry.
Abstract
The lanthanide complex, thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (TmDOTA-), has been investigated as an agent for MR thermometry in vivo. The chemical shifts of the TmDOTA- protons were highly sensitive to temperature at a clinically relevant field strength, yet insensitive to pH and the presence of Ca2+. Given the excellent stability of lanthanide-DOTA complexes and high thermal sensitivity, TmDOTA- is expected to be a good candidate for MR thermometry in vivo. Copyright 2001 Academic Press.Entities:
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Year: 2001 PMID： 11444943 DOI： 10.1006/jmre.2001.2356
Source DB: PubMed Journal: J Magn Reson ISSN： 1090-7807 Impact factor: 2.229