Literature DB >> 11435143

Effects of pulmonary afterload on the hemodynamics after the hemi-Fontan procedure.

G Guadagni1, E L Bove, F Migliavacca, G Dubini.   

Abstract

A computational fluid dynamics study based on the application of the finite volume method has been performed to investigate the effects of the pulmonary afterload on the hemodynamics after the hemi-Fontan procedure. This operation is generally used as part of a series of staged procedures to treat complex congenital malformations of the heart. It consists of re-directing the superior vena caval flow from the right atrium into the pulmonary arteries, by-passing the right ventricle while excluding the inferior caval flow from the lungs. To reproduce correctly the pulmonary afterload conditions, a simplified lumped-parameter mechanical model of the pulmonary circulation has been developed and linked to the finite volume solver. In addition, the effect of a stenosis in the left pulmonary artery was also examined. In this paper the adopted methodology is presented, together with some of the preliminary results. The model has been used to simulate the local fluid dynamics for different values of the pulmonary arteriolar resistance and lung resistances, allowing a quantitative evaluation of the dissipated energy and the flow distribution into the lungs. The results show that both flow distribution into the lungs and energy dissipation after the hemi-Fontan procedure are only minimally affected by the pulmonary arteriolar resistance.

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Year:  2001        PMID: 11435143     DOI: 10.1016/s1350-4533(01)00035-2

Source DB:  PubMed          Journal:  Med Eng Phys        ISSN: 1350-4533            Impact factor:   2.242


  5 in total

1.  Wall shear stress is the primary mechanism of energy loss in the Fontan connection.

Authors:  K R Moyle; G D Mallinson; C J Occleshaw; B R Cowan; T L Gentles
Journal:  Pediatr Cardiol       Date:  2006 May-Jun       Impact factor: 1.655

Review 2.  Toward optimal hemodynamics: computer modeling of the Fontan circuit.

Authors:  E L Bove; M R de Leval; F Migliavacca; R Balossino; G Dubini
Journal:  Pediatr Cardiol       Date:  2007 Nov-Dec       Impact factor: 1.655

3.  In vitro hemodynamic investigation of the embryonic aortic arch at late gestation.

Authors:  Kerem Pekkan; Lakshmi P Dasi; Paymon Nourparvar; Srinivasu Yerneni; Kimimasa Tobita; Mark A Fogel; Bradley Keller; Ajit Yoganathan
Journal:  J Biomech       Date:  2008-05-07       Impact factor: 2.712

Review 4.  Modeling the Fontan circulation: where we are and where we need to go.

Authors:  C G DeGroff
Journal:  Pediatr Cardiol       Date:  2007-10-05       Impact factor: 1.655

5.  Numerical Simulation of Hemodynamics in Two Models for Total Anomalous Pulmonary Venous Connection Surgery.

Authors:  Yeyang Cheng; Aike Qiao; Yao Yang; Xiangming Fan
Journal:  Front Physiol       Date:  2020-03-10       Impact factor: 4.566

  5 in total

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