Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The function and synthesis of ribosomes.

Literature DB >> 11433365

The function and synthesis of ribosomes.

Abstract

Structural analyses of the large and small ribosomal subunits have allowed us to think about how they work in more detail than ever before. The mechanisms that underlie ribosomal synthesis, translocation and catalysis are now being unravelled, with practical implications for the design of antibiotics.

Mesh：

Substances：
RNA
Peptidyl Transferases

Year: 2001 PMID： 11433365 DOI： 10.1038/35080045

Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444

Keyword Cloud
Cited

76 in total

1. Proteomic approach to understanding antibiotic action.

Authors: Julia Elisabeth Bandow; Heike Brötz; Lars Ingo Ole Leichert; Harald Labischinski; Michael Hecker
Journal: Antimicrob Agents Chemother Date: 2003-03 Impact factor: 5.191

2. A novel conserved RNA-binding domain protein, RBD-1, is essential for ribosome biogenesis.

Authors: Petra Björk; Göran Baurén; ShaoBo Jin; Yong-Guang Tong; Thomas R Bürglin; Ulf Hellman; Lars Wieslander
Journal: Mol Biol Cell Date: 2002-10 Impact factor: 4.138

3. Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP.

Authors: Nicholas J Watkins; Achim Dickmanns; Reinhard Lührmann
Journal: Mol Cell Biol Date: 2002-12 Impact factor: 4.272

Review 4. The ribosome filter hypothesis.

Authors: Vincent P Mauro; Gerald M Edelman
Journal: Proc Natl Acad Sci U S A Date: 2002-09-09 Impact factor: 11.205

5. Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification.

Authors: Christophe Dez; Carine Froment; Jacqueline Noaillac-Depeyre; Bernard Monsarrat; Michèle Caizergues-Ferrer; Yves Henry
Journal: Mol Cell Biol Date: 2004-07 Impact factor: 4.272

10. Normalization with genes encoding ribosomal proteins but not GAPDH provides an accurate quantification of gene expressions in neuronal differentiation of PC12 cells.

Authors: Lihan Zhou; Qing-En Lim; Guoqiang Wan; Heng-Phon Too
Journal: BMC Genomics Date: 2010-01-29 Impact factor: 3.969

The function and synthesis of ribosomes.

1. Proteomic approach to understanding antibiotic action.

2. A novel conserved RNA-binding domain protein, RBD-1, is essential for ribosome biogenesis.

3. Conserved stem II of the box C/D motif is essential for nucleolar localization and is required, along with the 15.5K protein, for the hierarchical assembly of the box C/D snoRNP.

Review 4. The ribosome filter hypothesis.

5. Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification.

6. Dim2p, a KH-domain protein required for small ribosomal subunit synthesis.

7. The evolutionarily conserved protein Las1 is required for pre-rRNA processing at both ends of ITS2.

Review 8. A census of human RNA-binding proteins.

9. The von Hippel-Lindau protein pVHL inhibits ribosome biogenesis and protein synthesis.

10. Normalization with genes encoding ribosomal proteins but not GAPDH provides an accurate quantification of gene expressions in neuronal differentiation of PC12 cells.