Literature DB >> 11429322

MICA and MICB genes: can the enigma of their polymorphism be resolved?

H A Stephens1.   

Abstract

The human MHC class I chain-related genes (MICA and MICB) are located within the HLA class I region of chromosome 6. Their organization, expression and products differ considerably from classical HLA class I genes. MIC proteins are considered to be markers of "stress" in the epithelia, and act as ligands for cells expressing a common activatory natural killer-cell receptor (NKG2D). Molecular models are now available for the MICA protein, both bound and complexed with NKG2D. MICA molecules appear to be highly flexible and polymorphic, although the functional relevance and implications of their polymorphism have yet to be fully discerned.

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Year:  2001        PMID： 11429322     DOI： 10.1016/s1471-4906(01)01960-3

Source DB:  PubMed          Journal:  Trends Immunol        ISSN： 1471-4906            Impact factor:   16.687


  55 in total

Review 1.  Induction of T cell alertness by bacterial colonization of intestinal epithelium.

Authors:  Thomas Spies
Journal:  Proc Natl Acad Sci U S A       Date:  2002-03-05       Impact factor: 11.205

2.  MICB typing by PCR amplification with sequence specific primers.

Authors:  Segundo González; Sandra Rodríguez-Rodero; Jesús Martínez-Borra; Antonio López-Vázquez; Luis Rodrigo; Carlos López-Larrea
Journal:  Immunogenetics       Date:  2003-03-06       Impact factor: 2.846

Review 3.  Expression of nonclassical MHC class Ib genes: comparison of regulatory elements.

Authors:  T Kevin Howcroft; Dinah S Singer
Journal:  Immunol Res       Date:  2003       Impact factor: 2.829

4.  Possible polyphyletic origin of major histocompatibility complex class I chain-related gene A (MICA) alleles.

Authors:  Mun-Kit Choy; Maude E Phipps
Journal:  J Mol Evol       Date:  2003-07       Impact factor: 2.395

5.  Genomic evolution of MHC class I region in primates.

Authors:  Kaoru Fukami-Kobayashi; Takashi Shiina; Tatsuya Anzai; Kazumi Sano; Masaaki Yamazaki; Hidetoshi Inoko; Yoshio Tateno
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-20       Impact factor: 11.205

6.  Genomic location and characterisation of MIC genes in cattle.

Authors:  James Birch; Cristina De Juan Sanjuan; Efrain Guzman; Shirley A Ellis
Journal:  Immunogenetics       Date:  2008-06-12       Impact factor: 2.846

Review 7.  Vγ9Vδ2 T cell-based immunotherapy in hematological malignancies: from bench to bedside.

Authors:  Barbara Castella; Candida Vitale; Marta Coscia; Massimo Massaia
Journal:  Cell Mol Life Sci       Date:  2011-05-17       Impact factor: 9.261

8.  Major Histocompatibility Complex Class I Chain-Related A and B (MICA and MICB) Gene, Allele, and Haplotype Associations With Dengue Infections in Ethnic Thais.

Authors:  Panpimon Luangtrakool; Sasijit Vejbaesya; Komon Luangtrakool; Somporn Ngamhawornwong; Kusuma Apisawes; Siripen Kalayanarooj; Louis R Macareo; Stefan Fernandez; Richard G Jarman; Robert W M Collins; Steven T Cox; Anon Srikiatkhachorn; Alan L Rothman; Henry A F Stephens
Journal:  J Infect Dis       Date:  2020-08-04       Impact factor: 5.226

Review 9.  Immunogenetics of the NKG2D ligand gene family.

Authors:  Masanori Kasahara; Shigeru Yoshida
Journal:  Immunogenetics       Date:  2012-07-29       Impact factor: 2.846

10.  MICA variant promotes allosensitization after kidney transplantation.

Authors:  Pierre Tonnerre; Nathalie Gérard; Mathias Chatelais; Caroline Poli; Stéphanie Allard; Sylvie Cury; Céline Bressollette; Anne Cesbron-Gautier; Béatrice Charreau
Journal:  J Am Soc Nephrol       Date:  2013-03-28       Impact factor: 10.121
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