Literature DB >> 11428454

Relocating the site of frozen sections--is there room for improvement?

C J Kerawala1, T K Ong.   

Abstract

INTRODUCTION: In an attempt to improve the marginal control of oropharyngeal carcinoma, some surgeons routinely perform frozen section analysis. Because current methods of relocating the site from which frozen section specimens are harvested can be haphazard, we studied the accuracy of a common technique used to localize specimens to the resected tumour bed.
METHODS: One surgeon was asked to identify the sites of proposed sampling in 14 consecutive cases. After approximately 5 minutes, the same surgeon was asked to relocate each site.
RESULTS: In all, 71 soft tissue points were identified. The mean error in relocating the sample site was 9 mm for those placed at mucosal margins and 12 mm for those placed deep to the tumor bed. The error exceeded 1 cm in 32% (23 of 71) of cases.
CONCLUSION: These findings highlight the need to accurately locate the position of frozen sections if samples that subsequently prove positive are to used to greatest effect.

Entities:  

Mesh:

Year:  2001        PMID: 11428454     DOI: 10.1002/1097-0347(200103)23:3<230::aid-hed1023>3.0.co;2-v

Source DB:  PubMed          Journal:  Head Neck        ISSN: 1043-3074            Impact factor:   3.147


  15 in total

1.  Prognostic value of frozen section in t1, t2 carcinoma of oral cavity.

Authors:  Sandhya Gokavarapu; L M Chandrasekhara Rao; Sujit Chau Patnaik; Nagendra Parvataneni; K V V N Raju; Ravi Chander
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2014-10-21

Review 2.  Intraoperative Margin Assessment in Head and Neck Cancer: A Case of Misuse and Abuse?

Authors:  Mark W Kubik; Shaum Sridharan; Mark A Varvares; Dan P Zandberg; Heath D Skinner; Raja R Seethala; Simion I Chiosea
Journal:  Head Neck Pathol       Date:  2020-03-02

3.  Fluorescent Molecular Imaging Can Improve Intraoperative Sentinel Margin Detection in Oral Squamous Cell Carcinoma.

Authors:  Giri Krishnan; Nynke S van den Berg; Naoki Nishio; Shrey Kapoor; Jaqueline Pei; Laura Freeman; Yu-Jin Lee; Quan Zhou; Stan van Keulen; Shayan Farkurnejad; James Condon; Fred M Baik; Brock A Martin; Eben L Rosenthal
Journal:  J Nucl Med       Date:  2022-01-13       Impact factor: 11.082

Review 4.  Determining Adequate Margins in Head and Neck Cancers: Practice and Continued Challenges.

Authors:  Michelle D Williams
Journal:  Curr Oncol Rep       Date:  2016-09       Impact factor: 5.075

5.  Early Oral Tongue Squamous Cell Carcinoma: Sampling of Margins From Tumor Bed and Worse Local Control.

Authors:  Jessica H Maxwell; Lester D R Thompson; Margaret S Brandwein-Gensler; Bernhard G Weiss; Martin Canis; Bibianna Purgina; Arpan V Prabhu; Chi Lai; Yongli Shuai; William R Carroll; Anthony Morlandt; Umamaheswar Duvvuri; Seungwon Kim; Jonas T Johnson; Robert L Ferris; Raja Seethala; Simion I Chiosea
Journal:  JAMA Otolaryngol Head Neck Surg       Date:  2015-12       Impact factor: 6.223

6.  Improving margin revision: Characterization of tumor bed margins in early oral tongue cancer.

Authors:  Arpan V Prabhu; Charles D Sturgis; Chi Lai; Jessica H Maxwell; Mihai Merzianu; Juan C Hernandez-Prera; Bibianna Purgina; Lester D R Thompson; Madalina Tuluc; Xiu Yang; Raja R Seethala; Robert L Ferris; Simion I Chiosea
Journal:  Oral Oncol       Date:  2017-11-01       Impact factor: 5.337

Review 7.  Margin Analysis in Head and Neck Cancer: State of the Art and Future Directions.

Authors:  Michael M Li; Sidharth V Puram; Dustin A Silverman; Matthew O Old; James W Rocco; Stephen Y Kang
Journal:  Ann Surg Oncol       Date:  2019-08-05       Impact factor: 5.344

8.  The impact of frozen sections on final surgical margins in squamous cell carcinoma of the oral cavity and lips: a retrospective analysis over an 11 years period.

Authors:  Stefan Gerber; Carole Gengler; Klaus W Grätz; Astrid L Kruse
Journal:  Head Neck Oncol       Date:  2011-12-30

9.  The utility of intra-oral ultrasound in improving deep margin clearance of oral tongue cancer resections.

Authors:  Mustafa G Bulbul; Osama Tarabichi; Anuraag S Parikh; Byung C Yoon; Amy Juliano; Peter M Sadow; William Faquin; Matthew Gropler; Ronald Walker; Sidharth V Puram; Mark A Varvares
Journal:  Oral Oncol       Date:  2021-09-23       Impact factor: 5.972

10.  Impact of surgical margins on local control in patients undergoing single-modality transoral robotic surgery for HPV-related oropharyngeal squamous cell carcinoma.

Authors:  Andrew J Holcomb; Matthew Herberg; Madeleine Strohl; Edgar Ochoa; Allen L Feng; Nicholas B Abt; Tara E Mokhtari; Krish Suresh; Christopher I McHugh; Anuraag S Parikh; Peter Sadow; William Faquin; Daniel Faden; Daniel G Deschler; Mark A Varvares; Derrick T Lin; Carole Fakhry; William R Ryan; Jeremy D Richmon
Journal:  Head Neck       Date:  2021-04-15       Impact factor: 3.821

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