| Literature DB >> 11420724 |
C Demeret1, Y Vassetzky, M Méchali.
Abstract
Organization of DNA into chromatin is likely to participate in the control of the timing and selection of DNA replication origins. Reorganization of the chromatin is carried out by chromatin remodelling machines, which may affect the choice of replication origins and efficiency of replication. Replication itself causes a profound rearrangement in the chromatin structure, from nucleosomes to DNA loop domains, allowing to retain or switch an epigenetic state. The present review considers the effects of chromatin remodelling on replication and vice versa.Mesh:
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Year: 2001 PMID: 11420724 DOI: 10.1038/sj.onc.1204333
Source DB: PubMed Journal: Oncogene ISSN: 0950-9232 Impact factor: 9.867