Literature DB >> 11418580

Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21.

S T Gregory1, J H Cate, A E Dahlberg.   

Abstract

Spontaneous, erythromycin-resistant mutants of Thermus thermophilus IB-21 were isolated and found to carry the mutation A2058G in one of two 23S rRNA operons. The heterozygosity of these mutants indicates that A2058G confers a dominant or codominant phenotype in this organism. This mutation provides a valuable tool for the genetic manipulation of the 23S rRNA genes of Thermus.

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Year:  2001        PMID： 11418580      PMCID： PMC95329          DOI： 10.1128/JB.183.14.4382-4385.2001

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  32 in total

1.  The complete atomic structure of the large ribosomal subunit at 2.4 A resolution.

Authors:  N Ban; P Nissen; J Hansen; P B Moore; T A Steitz
Journal:  Science       Date:  2000-08-11       Impact factor: 47.728

2.  A plasmid-coded and site-directed mutation in Escherichia coli 23S RNA that confers resistance to erythromycin: implications for the mechanism of action of erythromycin.

Authors:  B Vester; R A Garrett
Journal:  Biochimie       Date:  1987-08       Impact factor: 4.079

3.  A compilation of large subunit (23S and 23S-like) ribosomal RNA structures: 1993.

Authors:  R R Gutell; M W Gray; M N Schnare
Journal:  Nucleic Acids Res       Date:  1993-07-01       Impact factor: 16.971

4.  Antibiotic resistance mutations in 16S and 23S ribosomal RNA genes of Escherichia coli.

Authors:  C D Sigmund; M Ettayebi; E A Morgan
Journal:  Nucleic Acids Res       Date:  1984-06-11       Impact factor: 16.971

5.  Mutations in 23S rRNA and ribosomal protein L4 account for resistance in pneumococcal strains selected in vitro by macrolide passage.

Authors:  A Tait-Kamradt; T Davies; M Cronan; M R Jacobs; P C Appelbaum; J Sutcliffe
Journal:  Antimicrob Agents Chemother       Date:  2000-08       Impact factor: 5.191

6.  Mutations in 23S rRNA are associated with clarithromycin resistance in Helicobacter pylori.

Authors:  J Versalovic; D Shortridge; K Kibler; M V Griffy; J Beyer; R K Flamm; S K Tanaka; D Y Graham; M F Go
Journal:  Antimicrob Agents Chemother       Date:  1996-02       Impact factor: 5.191

7.  Functional interactions within 23S rRNA involving the peptidyltransferase center.

Authors:  S Douthwaite
Journal:  J Bacteriol       Date:  1992-02       Impact factor: 3.490

8.  Ribosomal protein gene sequence changes in erythromycin-resistant mutants of Escherichia coli.

Authors:  H S Chittum; W S Champney
Journal:  J Bacteriol       Date:  1994-10       Impact factor: 3.490

9.  Genomic restriction map of the extremely thermophilic bacterium Thermus thermophilus HB8.

Authors:  K M Borges; P L Bergquist
Journal:  J Bacteriol       Date:  1993-01       Impact factor: 3.490

10.  Genetic transformation of the extreme thermophile Thermus thermophilus and of other Thermus spp.

Authors:  Y Koyama; T Hoshino; N Tomizuka; K Furukawa
Journal:  J Bacteriol       Date:  1986-04       Impact factor: 3.490
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  6 in total

1.  Mutations in a 23S rRNA gene of Chlamydia trachomatis associated with resistance to macrolides.

Authors:  O Y Misyurina; E V Chipitsyna; Y P Finashutina; V N Lazarev; T A Akopian; A M Savicheva; V M Govorun
Journal:  Antimicrob Agents Chemother       Date:  2004-04       Impact factor: 5.191

2.  A mutation in the decoding center of Thermus thermophilus 16S rRNA suggests a novel mechanism of streptomycin resistance.

Authors:  Steven T Gregory; Jennifer F Carr; Albert E Dahlberg
Journal:  J Bacteriol       Date:  2005-03       Impact factor: 3.490

3.  The origin of a derived superkingdom: how a gram-positive bacterium crossed the desert to become an archaeon.

Authors:  Ruben E Valas; Philip E Bourne
Journal:  Biol Direct       Date:  2011-02-28       Impact factor: 4.540

4.  Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus.

Authors:  Steven T Gregory; Jennifer F Carr; Daniel Rodriguez-Correa; Albert E Dahlberg
Journal:  J Bacteriol       Date:  2005-07       Impact factor: 3.490

5.  Genetic and structural analysis of base substitutions in the central pseudoknot of Thermus thermophilus 16S ribosomal RNA.

Authors:  Steven T Gregory; Albert E Dahlberg
Journal:  RNA       Date:  2009-02       Impact factor: 4.942

6.  Difficidin and bacilysin from Bacillus amyloliquefaciens FZB42 have antibacterial activity against Xanthomonas oryzae rice pathogens.

Authors:  Liming Wu; Huijun Wu; Lina Chen; Xinfang Yu; Rainer Borriss; Xuewen Gao
Journal:  Sci Rep       Date:  2015-08-13       Impact factor: 4.379
  6 in total

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